The New Anthelmintic Tribendimidine is an L-type (Levamisole and Pyrantel) Nicotinic Acetylcholine Receptor Agonist

August 11, 2009
4588 views
URL
Embed
Share

Please describe the reason for abuse:



Article:
Peer-Reviewed Paper, View Original
Description:
Background Intestinal parasitic nematodes such as hookworms, Ascaris lumbricoides, and Trichuris trichiura are amongst most prevalent... » More
Citation:
PLoS Negl Trop Dis. 2009 Aug 11; 3(8):e499
Authors:
Yan Hu, Shu-Hua Xiao, Raffi V. Aroian

Loading comments
  1. Hotez PJ (2008) . Forgotten people, forgotten diseases : the neglected tropical diseases and their impact on global health and development: xixASM Press. Washington, DC.
  2. Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE (2007) Control of neglected tropical diseases.. N Engl J Med 357: 1018-1027.
  3. Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A (2006) Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.. Lancet 367: 1521-1532.
  4. Albonico M, Allen H, Chitsulo L, Engels D, Gabrielli AF (2008) Controlling Soil-Transmitted Helminthiasis in Pre-School-Age Children through Preventive Chemotherapy.. PLoS Negl Trop Dis 2: e126.
  5. Hall A, Hewitt G, Tuffrey V, de Silva N (2008) A review and meta-analysis of the impact of intestinal worms on child growth and nutrition.. Matern Child Nutr 4: 118-236.
  6. Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ (2008) Helminth infections: the great neglected tropical diseases.. J Clin Invest 118: 1311-1321.
  7. Keiser J, Utzinger J (2008) Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis.. JAMA 299: 1937-1948.
  8. Smits HL (2009) Prospects for the control of neglected tropical diseases by mass drug administration.. Expert Rev Anti Infect Ther 7: 37-56.
  9. Kaplan RM (2004) Drug resistance in nematodes of veterinary importance: a status report.. Trends Parasitol 20: 477-481.
  10. Flohr C, Tuyen LN, Lewis S, Minh TT, Campbell J (2007) Low efficacy of mebendazole against hookworm in Vietnam: two randomized controlled trials.. Am J Trop Med Hyg 76: 732-736.
  11. Xiao SH, Hui-Ming W, Tanner M, Utzinger J, Chong W (2005) Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China.. Acta Trop 94: 1-14.
  12. Steinmann P, Zhou XN, Du ZW, Jiang JY, Xiao SH (2008) Tribendimidine and Albendazole for Treating Soil-Transmitted Helminths, Strongyloides stercoralis and Taenia spp.: Open-Label Randomized Trial.. PLoS Negl Trop Dis 2: e322.
  13. Zhang JH, Xiao SH, Wu ZX, Qiu DC, Wang SH (2008) Tribendimidine enteric coated tablet in treatment of 1,292 cases with intestinal nematode infection–a phase IV clinical trial.. Chin J Parasitol Parasit Dis 26: 6-9 in Chinese.
  14. Xiao SH, Jian X, Tanner M, Yong-Nian Z, Keiser J (2008) Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against Clonorchis sinensis: a comparative in vivo study.. Acta Trop 106: 54-59.
  15. Geary TG, Thompson DP (2001) Caenorhabditis elegans: how good a model for veterinary parasites?. Vet Parasitol 101: 371-386.
  16. Brenner S (1974) The genetics of Caenorhabditis elegans.. Genetics 77: 71-94.
  17. Driscoll M, Dean E, Reilly E, Bergholz E, Chalfie M (1989) Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity.. J Cell Biol 109: 2993-3003.
  18. Bischof LJ, Huffman DL, Aroian RV (2006) Assays for toxicity studies in C. elegans with Bt crystal proteins.. Methods Mol Biol 351: 139-154.
  19. Sulston J, Hodgkin J (1988) Methods.. The nematode Caenorhabditis elegans: 587-606Cold Spring Harbor Laboratory Press. Cold Spring Harbor, , NY.
  20. Davis MW, Hammarlund M, Harrach T, Hullett P, Olsen S (2005) Rapid single nucleotide polymorphism mapping in C. elegans.. BMC Genomics 6: 118.
  21. Griffitts JS, Whitacre JL, Stevens DE, Aroian RV (2001) Bt toxin resistance from loss of a putative carbohydrate-modifying enzyme.. Science 293: 860-864.
  22. Wei JZ, Hale K, Carta L, Platzer E, Wong C (2003) Bacillus thuringiensis crystal proteins that target nematodes.. Proc Natl Acad Sci U S A 100: 2760-2765.
  23. Kim J, Poole DS, Waggoner LE, Kempf A, Ramirez DS (2001) Genes affecting the activity of nicotinic receptors involved in Caenorhabditis elegans egg-laying behavior.. Genetics 157: 1599-1610.
  24. Martin RJ, Verma S, Levandoski M, Clark CL, Qian H (2005) Drug resistance and neurotransmitter receptors of nematodes: recent studies on the mode of action of levamisole.. Parasitology 131: S71-84.
  25. Jones AK, Buckingham SD, Sattelle DB (2005) Chemistry-to-gene screens in Caenorhabditis elegans.. Nat Rev Drug Discov 4: 321-330.
  26. Aroian RV, Levy AD, Koga M, Ohshima Y, Kramer JM (1993) Splicing in Caenorhabditis elegans does not require an AG at the 3′ splice acceptor site.. Mol Cell Biol 13: 626-637.
  27. Mount SM (1982) A catalogue of splice junction sequences.. Nucleic Acids Res 10: 459-472.
  28. Holden-Dye L, Walker RJ (2007) Anthelmintic drugs.. WormBook: 1-13.
  29. Lewis JA, Wu CH, Berg H, Levine JH (1980) The genetics of levamisole resistance in the nematode Caenorhabditis elegans.. Genetics 95: 905-928.
  30. Nguyen M, Alfonso A, Johnson CD, Rand JB (1995) Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase.. Genetics 140: 527-535.
  31. Dent JA, Davis MW, Avery L (1997) avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans.. EMBO J 16: 5867-5879.
  32. Dent JA, Smith MM, Vassilatis DK, Avery L (2000) The genetics of ivermectin resistance in Caenorhabditis elegans.. Proc Natl Acad Sci U S A 97: 2674-2679.
  33. Kaminsky R, Ducray P, Jung M, Clover R, Rufener L (2008) A new class of anthelmintics effective against drug-resistant nematodes.. Nature 452: 176-180.
  34. Touroutine D, Fox RM, Von Stetina SE, Burdina A, Miller DM (2005) acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction.. J Biol Chem 280: 27013-27021.
  35. Utzinger J, Keiser J (2004) Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control.. Expert Opin Pharmacother 5: 263-285.
  36. Albonico M, Bickle Q, Ramsan M, Montresor A, Savioli L (2003) Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar.. Bull World Health Organ 81: 343-352.
  37. Geerts S, Gryseels B (2001) Anthelmintic resistance in human helminths: a review.. Trop Med Int Health 6: 915-921.
Hu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Copyright 2014 © Yan Hu, Shu-Hua Xiao, Raffi V. Aroian. This pubcast is licensed under the terms of the Creative Commons Attribution License 3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.