Harnessing the Immune System to Fight Cancer

submitted by: mcgheek
With the entry of immune checkpoint inhibitors such as anti-PD1 and anti-CTLA-4 into the clinic, excitement about immune-based therapies for cancer has been growing. Three immunologists at the Medical University of South Carolina (MUSC)—Zihai Li, M.D., Ph.D., Shikhar Mehrotra, Ph.D., and Chrystal Paulos, Ph.D.—discuss the promise of immune-based therapies such as immune checkpoint blockade and adoptive cell transfer and how the researchers and clinicians at MUSC are helping advance the...

Tools to help you quit smoking for good

submitted by: mdanderson
Download on iTunes: https://itunes.apple.com/us/podcast/tools-to-help-you-quit-smoking/id431... It isn't easy to quit smoking, and often it takes more than one approach to be successful. In this episode, Maher Karam-Hage, M.D., professor of Behavioral Science, outlines several tools available to those who want to quit smoking for good.

Innovations in Left Ventricular Assist Device (LVAD) Technology

submitted by: mcgheek

Dr. John Ikonomidis, Chief of the Cardiothoracic Surgery at MUSC Health, discusses innovations (smaller devices, pulsatile technology) in Left Ventricular Assist Device (LVAD) technology and how the LVAD can act as bridge therapy for patients seeking a heart transplant.

Pirfenidone and Nintedanib: Tips for Treating Patients with Idiopathic Pulmonary Fibrosis

submitted by: mcgheek

Dr. Timothy Whelan, Medical Director of the Lung Transplant Program from the Medical University of South Carolina, provides advice for 2 new drugs Pirfenidone and Nintedanib designed to slow the progression of idiopathic pulmonary fibrosis.

Management of periodontal disease in patients using calcium channel blockers – gingival overgrowth, prescribed medications, treatment responses and added treatment costs

submitted by: fardal
Abstract Objectives Gingival overgrowth (GO) is an adverse drug reaction in patients using calcium channel blockers (CCBs). Little is known about the effects of CCBs on the management of periodontal diseases. The aim of this study was to assess how the use of CCBs affects the long-term supportive treatment and outcomes in patients undergoing periodontal therapy. Methods All patients using CCBs during the initial treatment and/or the supportive periodontal therapy (SPT) were selected...
Authors: Øystein Fardal, Henning Lygre

Apical periodontitis and incident cardiovascular events in the Baltimore Longitudinal Study of Ageing

submitted by: endomax
Aim: To evaluate whether the presence of apical periodontitis (AP), root canal treatment (RCT) and endodontic burden (EB) – as the sum of AP and RCT sites – were associated with long-term risk of incident cardiovascular events (CVE), including cardiovascular-related mortality, using data on participants in the Baltimore Longitudinal Study of Ageing (BLSA). Methodology: This retrospective cohort included 278 dentate participants in the BLSA with complete medical and dental examinations....
Authors: Maximiliano Gomes, Fernando Hugo, Juliana Hilgert, Manoel Sant´Ana Filho, Dalva Padilha, Eleanor Simonsick, Luigi Ferrucci, Mark Reynolds