iCONCUR: informed CONsent for Clinical data Use for Research Date: Fri May 17, 2013 Host: Lucila Ohno-Machado University of California San Diego ABSTRACT Biomedical research and healthcare improvements are accelerating through the sharing of data and use of predictive analytics on these data. Sources of data include electronic health record systems, clinical trial management systems, and personal monitoring devices—each with its own regulations for data use in research and quality...

A reduction in the generation of lung-homing TB-specific effector memory CD4 Th1 cells after HIV infection is a key factor in the increased risk of active TB disease. Natural killer T cells are an innate type of immune cells responsible for first line of anti-viral defense, which may “jump-start” the adaptive immune responses and regulate the Th1 versus Th2 differentiation of CD4 helper T cells, through their unique ability to activate antigen-presenting cells (e.g., DCs). The regulatory...

In an article appearing in the May 2013 issue of Mayo Clinic Proceedings, Dr. Mark A. Yarborough from the University of California, Davis, proposes the need to develop better disclosure, transparency, and measures of social value for persons recruited to participate in clinical research. Available at: http://tinyurl.com/d8appv7

Dr. James Stone, a Clinical Professor of Medicine at the University of Calgary, Canada, promotes the necessity, positive benefits, and overall mortality reduction with cardiac rehabilitation in patient with coronary artery disease as noted in their article appearing in the May 2013 issue of Mayo Clinic Proceedings. Available at: http://tinyurl.com/boopj26

Dr. Gregory Ruhnke, an Assistant Professor in the Section of Hospital Medicine at the University of Chicago, in an article coauthored with Dr. David Doukas appearing in the May 2013 issue of Mayo Clinic Proceedings, examines the context and professional implications of residents preparing for board examinations using questions reproduced by previous residents. Available at: http://tinyurl.com/c5dhms6

Dr. Kamyar Kalantar-Zadeh, a Professor of Medicine, Pediatrics and Epidemiology from the Harold Simmons Center for Kidney Disease Research and Epidemiology at the University of California, Irvine, in Orange, CA, reveals results of a study reported in the May 2013 issue of Mayo Clinic Proceedings that expands the understanding of the obesity paradox across multiple ethnicities. Available at: http://tinyurl.com/cotwsdd