biosights: September 1, 2014 - Deploying exosomes in a battle of the sexes

submitted by: JCB
The paired accessory glands of male Drosophila secrete multiple signaling factors into the seminal fluid that promote reproductive success by altering the recipient female's physiology and behavior. Corrigan et al. reveal that the secondary cells of accessory glands secrete membrane-bound exosomes in a BMP-dependent manner that, after being transferred into the female reproductive tract, inhibit the female's inclination to re-mate with other male flies. This biosights episode presents the...

biosights: August 4, 2014 - Rok keeps its finger on the pulse of apical constriction

submitted by: JCB
Early in Drosophila embryogenesis, contractile pulses of myosin assembly and disassembly constrict the apical domains of a group of epithelial cells to drive their invagination into a ventral furrow. Vasquez et al. reveal that Rho kinase and myosin phosphatase dynamically regulate these myosin pulses and that the stepwise constriction resulting from this helps maintain tissue integrity during epithelial invagination. This biosights episode presents the paper by Vasquez et al. from the August...

HERESY AND MEDICINE IN THE MIDDLE AGES

submitted by: camdic

"I fought a lot; I thought I could win, but fate and nature repressed my study and my efforts. But it is already something to be on the battlefield, because to win depends very much on fortune. But I did as much as I could, and I do not think anyone, of the future generation, will deny it. I was not afraid of death, I never gave in to anyone, I chose courageous death instead of a coward’s life". Giordano Bruno, De Monade (1591).

Annalee Newitz at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI

Annalee Newitz, io9, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Stephen Quake at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI

Steve Quake, Stanford University, at the 9th Annual Genomics of Energy & Environment Meeting on March 18, 2014 in Walnut creek, Calif.

Eddy Rubin at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI
Eddy Rubin, DOE JGI Director, at the 9th Annual Genomics of Energy & Environment Meeting on March 19, 2014 in Walnut Creek, Calif. The talk is related to a study published in the journal Science - details at http://jgi.doe.gov/glimpse-natures-looking-glass-to-find-the-genetic-cod... .