Immunotherapy: unleashing immune system to attack cancer

submitted by: mdanderson
Cancer immunotherapy treats the immune system rather than the tumor. Jim Allison, Ph.D., professor in Immunology at MD Anderson Cancer Center, has developed an innovative approach that will open doors for treating all types of cancer. Padmanee Sharma, M.D., Ph.D., associate professor in Genitourinary Medical Oncology and Immunology, is lead scientist on immunotherapy clinical trials. Listen to Allison and Sharma discuss their collaboration on MD Anderson’s Moon Shots Program to develop...

PharmGenEd™ Principles and Concepts of Pharmacogenomics

submitted by: KuoOffice

The presentation is divided into several sections as outlined by the powerpoint slide. In this module we will include the basic concepts of pharmacogenomics, ethical, legal, social issues, and a brief introduction of the PharmGenEd program.

MUSC Plastic Surgeons Target the Nerves That Trigger Migraine Headaches

submitted by: mcgheek

The Advanced Migraine Surgery Program (AMSP) at MUSC offers relief to individuals who suffer from migraine headaches and occipital neuralgia. One of the treatment options is surgery that relieves pressure on the facial and scalp nerves that can cause migraine headaches. In this video, Dr. Kevin O. Delaney, Assistant Professor of Plastic Surgery and one of the plastic surgeons who perform this surgery, describes the procedure and the overwhelmingly positive patient outcomes.

Saving Breath: Diagnosing and Managing COPD

submitted by: mcgheek

Luca Paoletti, M.D., a pulmonologist at the Medical University of South Carolina, discusses best practices for diagnosing (eg, spirometry, alpha-1 antitrypsin deficiency testing) and managing chronic obstructive pulmonary disease. Pulmonary rehabilitation is recommended for all COPD patients. Bronchodilators are the mainstay of medication therapy, and, for patients with medication-refractory COPD, lung volume reduction surgery and lung transplant are options.

Surgical periodontal therapy with and without initial scaling and root planing in the management of chronic periodontitis: a randomized clinical trial

submitted by: drmanar
Aim: To compare the outcomes of surgical periodontal therapy with and without initial scaling and root planing. Methods: Twenty-four patients with severe chronic periodontitis were enrolled in this pilot, randomized controlled clinical trial. Patients were equally allocated into two treatment groups: Control group was treated with scaling and root planing, re-evaluation, followed by Modified Widman Flap surgery and test group received similar surgery without scaling and root planing....
Authors: Manar Aljateeli

BMI and all-cause mortality in older adults: a meta-analysis

submitted by: winterj
Background: Whether the association between body mass index (BMI) and all-cause mortality for older adults is the same as for younger adults is unclear. Objective: The objective was to determine the association between BMI and all-cause mortality risk in adults ?65 y of age. Design: A 2 stage random-effects meta-analysis was performed of studies published from 1990 to 2013 that reported the RRs of all-cause mortality for community-based adults aged ?65 y. Results: Thirty-two studies met...
Authors: Jane Winter, Robert MacInnis, Naiyana Wattanapenpaiboon, Caryl Nowson