biosights: April 14, 2014 - An actin lever flattens out the cell

submitted by: JCB
The lamella is a broad, flat region that forms at the front of migrating cells and adheres to the underlying substrate. Burnette et al. reveal that cells flatten out the lamella by mechanically coupling a contractile actomyosin network at the dorsal surface to ventral cell adhesions. This biosights episode presents the paper by Burnette et al. from the April 14, 2014, issue of The Journal of Cell Biology and includes an interview with authors Dylan Burnette (Vanderbilt University School of...

Rotating Egg

submitted by: hsrikm

Graph of an egg derived from an equation and uneven unique angular periods from division of pi by whole numbers.

biosights: March 17, 2014 - Blebs lead the way in Dictyostelium chemotaxis

submitted by: JCB
Membrane blebs can help the leading edge of migrating cells protrude forwards, but the contribution of blebs to the motility of Dictyostelium cells is unclear. Zatulovskiy et al. reveal that blebs form at the front of chemotaxing Dictyostelium cells, particularly when the cells are faced with a mechanically resistant environment, and that this process is guided by a PI3-kinase-dependent signaling pathway. This biosights episode presents the paper by Zatulovskiy et al. from the March 17,...

How can yoga benefit women with breast cancer?

submitted by: mdanderson
New study shows yoga can regulate stress hormones and improve quality of life for women with breast cancer undergoing radiation therapy. For women with breast cancer undergoing radiation therapy, yoga offers unique benefits beyond fighting fatigue, according to research from The University of Texas MD Anderson Cancer Center. The preliminary findings were first reported in 2011 by Lorenzo Cohen, Ph.D., professor and director of the Integrative Medicine Program at MD Anderson, and are now...

Cultures Magazine Launch Event - MWV84

submitted by: MicrobeWorld

Watch highlights from the Cultures Magazine Launch Event held on January 23, 2014 at American Society for Microbiology headquarters in Washington, D.C.

Cultures is a free, online, open-source publication available for viewing at www.asm.org/cultures.

2/21/14 iDASH External Webinar; Jane Burns

submitted by: ucsd_idash
How genetic and genomic analysis are leading to new therapies in Kawasaki disease Jane Burns UCSD School of Medicine, Department of Pediatrics Abstract: Our first genetic studies of Kawasaki disease (KD) began in 1998 when we found a skewed distribution of two single nucleotide polymorphisms (SNPs) in the promoter region of TNF? that were potentially implicated in increased gene expression. These early observations inspired a small clinical trial of pentoxifylline, a modulator of TNF?...