Minimally invasive surgery treating cancer

submitted by: mdanderson
Minimally invasive, or endoscopic, surgery takes advantage of advances in computer imaging and robotics to provide effective surgical cancer treatment with a much smaller impact on the patient. Surena Matin, M.D., medical director of the Minimally Invasive and New Technology in Oncologic Surgery (MINTOS) Collaborative Group at MD Anderson Cancer Center, discusses treatment options using this treatment option for diseases such as prostate cancer, kidney cancer, bladder cancer and gynecologic...

biosights: February 16, 2015 - Filopodia point the way for haptotaxis

submitted by: JCB
Migrating fibroblasts maintain or change their direction by branching off new lamellipodia from existing protrusions at the cell's leading edge. Johnson et al. reveal that filopodial protrusions initiate and orient these lamellipodia, helping fibroblasts navigate gradients of immobilized guidance cues. This biosights episode presents the paper by Johnson et al. from the February 16, 2015, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Jason...

biosights: January 19, 2015 - Tubulin transport pumps up cilia

submitted by: JCB
The assembly of cilia and flagella requires the delivery of large amounts of tubulin to the growing ends of the organelles' microtubules. Craft et al. reveal that tubulin loading onto intraflagellar transport particles is specifically upregulated in growing cilia. This biosights episode presents the paper by Craft et al. from the January 19, 2015, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Karl Lechtreck (University of Georgia, Athens, GA)....

biosights: December 22, 2014 - Osmotic gradient is just the tonic for wounded epithelia

submitted by: JCB
Rapid wound repair is generally thought to be initiated by intrinsic cues, such as changes in the structure or mechanics of damaged tissues. Gault et al. reveal that an extrinsic signal — the osmolarity of the external environment — can stimulate wound closure in zebrafish by inducing epithelial cell migration. This biosights episode presents the paper by Gault et al. from the December 22, 2014, issue of The Journal of Cell Biology and includes an interview with the paper's senior...

Avian Phylogenomics Consortium report details origins of bird species

submitted by: nsf
In a landmark study that researched the origins of bird species, evolutionary biologists have made discoveries about the age of birds, and the genomic relationships among modern birds. The genomes of modern birds tell a story: today's winged rulers of the skies emerged and evolved after the mass extinction that wiped out dinosaurs and almost everything else 66 million years ago. That story is now coming to light, thanks to an international collaboration that has been underway for four...

Conserving biodiversity in Central Africa

submitted by: nsf
The Congo basin is an unruly ribbon of tropical forest, over a million square miles spanning six countries in Central Africa. It is the second-largest contiguous tropical forest in the world. The basin is home to the classics of African wildlife – chimpanzees, elephants, gorillas – along with thousands of other less well-known species. This wealth of flora and fauna, much of it native to the region, is enough to qualify the Congo basin as a biodiversity hotspot: a biologically rich...