Grape Powder Supplementation Prevents Oxidative Stress–Induced Anxiety-Like Behavior, Memory Impairment, and High Blood Pressure in Rats

submitted by: ssalim
We examined whether or not grape powder treatment ameliorates oxidative stress–induced anxiety-like behavior, memory impairment, and hypertension in rats. Oxidative stress in Sprague-Dawley rats was produced by using L-buthionine- (S,R)-sulfoximine (BSO). Four groups of rats were used: 1) control (C; injected with vehicle and provided with tap water), 2) grape powder–treated (GP; injected with vehicle and provided for 3 wk with 15 g/L grape powder dissolved in tap water), 3)...
Authors: Farida Allam, An Dao, Gaurav Chugh, Ritu Bohat, Faizan Jafri, Gaurav Patki, Christopher Mowrey, Mohammad Asghar, Karim Alkadhi, Samina Salim

Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine

submitted by: Michelle Murphy
ABSTRACT Background: Folate, choline, and betaine participate in homocysteine metabolism. It is not known whether they interact during pregnancy. Objective: The objective was to investigate how folate status affects choline, betaine, and dimethylglycine during pregnancy. Design: Fasting plasma folate, cobalamin, free choline, betaine, dimethylglycine, and total homocysteine (tHcy) were measured longitudinally at ,12, 15, 24–27, and 34 gestational weeks (GW); at labor (nonfasting);...
Authors: Silvia Fernandez-Roig, Michelle M Murphy

Childhood Food Allergies: Current Diagnosis, Treatment, and Management Strategies

submitted by: WentzMR

In the May 2013 issue of Mayo Clinic Proceedings, available at: http://tinyurl.com/c7tp8jb
Dr. Ruchi Gupta, an Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicine and Ann & Robert H Lurie Children's Hospital of Chicago in IL, interprets recently published guidelines on childhood food allergies to aid clinicians in their practice.

Association of raw fruit and fruit juice consumption with blood pressure: the INTERMAP Study

submitted by: loudegri
Background: Epidemiological evidence suggests that fruit consumption may lower the risk of cardiovascular diseases through blood pressure (BP)–lowering effects; little is known on the independent effect of raw fruit and fruit juice on BP. Objective: The objective was to quantify associations of raw fruit and fruit juice consumption with BP by using cross-sectional data from the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP) of 4680 men and women aged...
Authors: Linda Oude Griep, Jeremiah Stamler, Queenie Chan, Linda Van Horn, Lyn Steffen, Katsuyuki Miura, Hirotsugu Ueshima, Nagako Okuda, Liancheng Zhao, Martha Daviglus, Paul Elliott

Weight loss, weight maintenance, and adaptive thermogenesis

submitted by: stefancamps
Background: Diet-induced weight loss is accompanied by adaptive thermogenesis, ie, a disproportional or greater than expected reduction of resting metabolic rate (RMR). Objective: The aim of this study was to investigate whether adaptive thermogenesis is sustained during weight maintenance after weight loss. Design: Subjects were 22 men and 69 women [mean 6 SD age: 40 6 9 y; body mass index (BMI; in kg/m2): 31.9 6 3.0]. They followed a very-low-energy diet for 8 wk, followed by a...
Authors: Stefan Camps, Sanne Verhoef, Klaas Westerterp

Dietary patterns and risk of dementia in an elderly Japanese population: the Hisayama Study

submitted by: Mio
ABSTRACT Background: To our knowledge, there are no previous reports that assessed the association between dietary patterns and risk of dementia in Asian populations. Objective: We investigated dietary patterns and their potential association with risk of incident dementia in a general Japanese population. Design: A total of 1006 community-dwelling Japanese subjects without dementia, aged 60–79 y, were followed up for a median of 15 y. The reduced rank regression procedure was used to...
Authors: Mio Ozawa, Toshiharu Ninomiya, Tomoyuki Ohara, Yasufumi Doi, Kazuhiro Uchida, Tomoko Shirota, Koji Yonemoto, Takanari Kitazono, Yutaka Kiyohara