Cobalamin supplementation improves motor development and regurgitations in infants: results from a randomized intervention study

Background: During infancy, minor developmental delays and gas- trointestinal complaints are common, as is a biochemical profile in- dicative of impaired cobalamin status. Objective: We investigated whether cobalamin supplementation can improve development or symptoms in infants with biochemical signs of impaired cobalamin function and developmental delay or feeding difficulties. Design: Infants ,8 mo of age (n = 105) who were referred for feeding difficulties, subtle neurologic...
Authors: Anne-Lise Bjørke-Monsen, Trond Markestad, Ingrid Torsvik, Per Magne Ueland

Belief beyond the evidence: using the presumed effect of breakfast on obesity

submitted by: awbrown
Background: Various intentional and unintentional factors in?uence beliefs beyond what scienti?c evidence justi?es. Two such factors are research lacking probative value (RLPV) and biased research reporting (BRR). Objective: We investigated the prevalence of RLPV and BRR in research about the proposition that skipping breakfast causes weight gain, which is called the proposed effect of breakfast on obesity (PEBO) in this article. Design: Studies related to the PEBO were synthesized...
Authors: David Allison, Michelle Bohan Brown, Andrew Brown

Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study

Aim The aim of this randomized placebo-controlled clinical trial was to evaluate the effects of Lactobacillus reuteri-containing probiotic lozenges as an adjunct to scaling and root planing (SRP). Material and Methods Thirty chronic periodontitis patients were recruited and monitored clinically and microbiologically at baseline, 3, 6, 9 and 12 weeks after therapy. All patients received one-stage full-mouth disinfection and randomly assigned over a test (SRP + probiotic, n = 15) or...
Authors: Wim Teughels, Andac Durukan, Onur Ozcelik, Martine Pauwels, Marc Quirynen, Mehmet Cenk Haytac

Evidence-Based Strategies in Weight Loss Mobile Apps

submitted by: spagoto
Background: Physicians have limited time for weight-loss counseling, and there is a lack of resources to which they can refer patients for assistance with weight loss. Weight-loss mobile applications (apps) have the potential to be a helpful tool, but the extent to which they include the behavioral strategies included in evidence-based interventions is unknown. Purpose: The primary aims of the study were to determine the degree to which commercial weightloss mobile apps include the...
Authors: Sherry Pagoto, Kristin Schneider, Mirjana Jojic, Michelle DeBiasse, Devin Mann

Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis

submitted by: vmalik
Background: The relation between sugar-sweetened beverages (SSBs) and body weight remains controversial. Objective: We conducted a systematic review and meta-analysis to summarize the evidence in children and adults. Design: We searched PubMed, EMBASE, and Cochrane databases through March 2013 for prospective cohort studies and randomized controlled trials (RCTs) that evaluated the SSB-weight relation. Separate meta-analyses were conducted in children and adults and for cohorts and...
Authors: Vasanti Malik, An Pan, Walter Willett, Frank Hu

Geospatial Exposure to Point-of-Sale Tobacco: Real-time craving and smoking-cessation outcomes

submitted by: tomkirchner
Background: Little is known about the factors that drive the association between point-of-sale marketing and behavior, because methods that directly link individual-level use outcomes to real-world point-of-sale exposure are only now beginning to be developed. Purpose: Daily outcomes during smoking cessation were examined as a function of both real-time geospatial exposure to point-of-sale tobacco (POST) and subjective craving to smoke. Methods: Continuous individual geospatial location data...
Authors: Thomas Kirchner, Jennifer Cantrell, Andrew Anesetti-Rothermel, Ollie Ganz, Donna Vallone, David Abrams