Defining UPLB’s Role in Philippine Plant Natural Products’ Research and Development in the Early 21st Century

submitted by: UP Los Baños

Documentation of the UPLB Centennial Professorial Lecture on "Defining UPLB’s Role in Philippine Plant Natural Products’ Research and Development in the Early 21st Century" by Dr. Lourdes B. Cardenas, Professor, Institute of Biological Sciences, College of Arts and Sciences, UP Los Baños on February 26, 2013 at the SEARCA Drilon Hall, UPLB, College, Laguna, Philippines.

Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studies

submitted by: Geoffrey Livesey
Background: Although much is known about the association between dietary glycemic load (GL) and type 2 diabetes (T2D), prospective cohort studies have not consistently shown a positive dose-response relation. Objective: We performed a comprehensive examination of evidence on the dose response that links GL to T2D and sources of heterogeneity among all prospective cohort studies on healthy adults available in the literature. Design: We conducted a systematic review of all prospective...
Authors: Geoffrey Livesey, Richard Taylor, Helen Livesey, Simin Liu

Cancer prevention: what is energy balance?

submitted by: mdanderson
What is energy balance? It may sound like a strange term, but it basically means equalizing the amount of calories you take in with how much you burn through exercise, metabolism and body processes. Since obesity is one of the leading causes of cancer, Carrie Daniel-MacDougall, Ph.D., M.P.H. and Susan Schembre, Ph.D., R.D., both assistant professors in Cancer Prevention and Population Sciences at MD Anderson Cancer Center, study behaviors and biological processes associated with linking...

Multivitamin-multimineral supplementation and mortality: A meta-analysis of randomized controlled trials

submitted by: mpase
Background: Multivitamins are the most commonly used supplement in the developed world. Recent epidemiological findings suggest multivitamin use increases the risk of mortality. Objectives: We aimed to determine whether multivitamin-multimineral treatment, used for primary or secondary prevention, increases the risk of mortality in independently living adults. Methods: We performed a meta-analysis of randomized, controlled trials. Multiple electronic databases were systematically searched...
Authors: Helen Macpherson, Andrew Pipingas, Matthew Pase

Aptamer Data from Base Pair Biotechnologies

submitted by: BasePairBio

Aptamers have until recently been tightly held by IP restrictions, Base Pair Biotechnologies Founder Bill Jackson presents information and data they have generated on aptmers in diverse assays such as biosensor and lateral flow. Presentation is from the American Society for Cell Biology meeting Dec 16, 2012

Birth weight of Korean infants is affected by the interaction of maternal iron intake and GSTM1 polymorphism

submitted by: jinhee.hur
Excessive iron consumption during pregnancy can lead to increased oxidative stress in the maternal body, which may result in adverse pregnancy outcomes. Glutathione S-transferases (GSTs) originate from a superfamily of detoxifying enzymes that play a role in reducing xenobiotic compounds and oxidative stress. The aim of this study was to determine the relationship among GST gene expression, maternal iron intake during pregnancy, and neonatal birth weight. The study participants were 1087...
Authors: Jinhee Hur, Hyesook Kim, Eun-Hee Ha, Hyesook Park, Mina Ha, Yangho Kim, Yun-Chul Hong, Namsoo Chang