High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial

submitted by: Vin_Tangpricha
Background: Vitamin D deficiency contributes to secondary hyperparathyroidism, which occurs early in chronic kidney disease (CKD). Objectives: We aimed to determine whether high-dose cholecalciferol supplementation for 1 y in early CKD is sufficient to maintain optimal vitamin D status (serum 25-hydroxyvitamin D [25(OH)D] concentration $30 ng/mL) and decrease serum parathyroid hormone (PTH). A secondary aim was to determine the effect of cholecalciferol on blood pressure and serum...
Authors: Jessica Alvarez, Jennie Law, Kathryn Coakley, Susu Zughaier, Li Hao, Khadijeh Salles, Haimanot Wasse, Orlando Gutiérrez, Thomas Ziegler, Vin Tangpricha

Pesticides and Herbicides: A Growing Concern (Webinar)

submitted by: Chrom Solutions
This webinar describes using suppressed ion chromatography--mass spectrometry (IC-MS/MS) for glyphosate (a widely used broad-spectrum herbicide) analysis with the result that required reporting limits can be achieved without time-consuming derivatization. In addition, a validated extraction method for weathered toxaphene (banned since 1990) and its degradation products in fish tissues using Accelerated Solvent Extraction is also discussed. Speakers: Diana Burdette (US EPA R4 SESD), Stuart...

Prepregnancy adherence to dietary patterns and lower risk of gestational diabetes mellitus

submitted by: dtobias
Abstract BACKGROUND: Previous studies observed inverse associations of adherence to the alternate Mediterranean (aMED), Dietary Approaches to Stop Hypertension (DASH), and alternate Healthy Eating Index (aHEI) dietary patterns with risk of type 2 diabetes; however, their associations with gestational diabetes mellitus (GDM) risk are unknown. OBJECTIVE: This study aimed to assess usual prepregnancy adherence to well-known dietary patterns and GDM risk. DESIGN: Our study included 21,376...
Authors: Deirdre Tobias, Cuilin Zhang, Jorge Chavarro, Katherine Bowers, Janet Rich-Edwards, Bernard Rosner, Dariush Mozaffarian, Frank Hu

1st Study of Trans Fats Ban in Annals of Internal Medicine

submitted by: YourUpdateTV

In 2006 New York City issued its unprecedented restrictions on the use of trans fats in fast food restaurants. Now the first study reporting the results of this restriction is being published in the Annals of Internal Medicine.

Effect of alginate supplementation on weight loss in obese subjects completing a 12-wk energy-restricted diet: a randomized controlled trial

submitted by: mekr@life.ku.dk
Background: Acute studies with alginate-based preloads suggested that these strong gelling fibers may induce increased feelings of satiety and reduce energy intakes. However, the long-term efficacy and safety of alginate supplementation on body weight regulation are lacking. Objective: The primary aim of the study was to investigate the effects in subjects of alginate supplementation in conjunction with energy restriction (2300 kcal/d) on loss of body weight and fat and, second, on...
Authors: Morten Georg Jensen, Mette Kristensen, Arne Astrup

Changes in Erythrocyte Membrane Trans and Marine Fatty Acids between 1999 and 2006 in Older Americans.

submitted by: jpolreis
Over the last several years, national programs to lower the content of industrially produced (IP) C18:1 and C18:2 trans fatty acids in foods have been implemented, but whether this has resulted in lower blood trans fatty acid levels is unknown. Likewise, an increased perception of the health benefits of fish oils rich in EPA and DHA may have resulted in an increase in consumption and blood levels of these fatty acids. To explore these issues, we analyzed the changes in RBC fatty acid...
Authors: WS Harris, JV Pottala