humans

Transfected Lysate (Native)

submitted by: abnova
by Abnova - Transfected lysate is useful as a positive control in Western Blot. The full-length protein construct is expressed in HEK293T cells and prepared as ready-to-use, native lysate in modified RIPA Buffer.

Tree of Life

submitted by: Treeoflife
Explore the evolutionary links between living things with the Wellcome Trust's Tree of Life, developed as part of our Darwin 200 activities, which celebrate the 200th anniversary of Charles Darwin's birth. This six-minute Tree of Life video also appeared on the BBC One programme 'Charles Darwin and the Tree of Life' narrated by David Attenborough. In addition to the video, an interactive version of the 'Tree of Life' here (http://www.wellcometreeoflife.org) has been created to allow...

The R403Q Myosin Mutation Implicated in Familial Hypertrophic Cardiomyopathy Causes Disorder at the Actomyosin Interface

submitted by: apryl
Authors: Niels Volkmann, HongJun Lui, Larnele Hazelwood, Kathleen M. Trybus, Susan Lowey, Dorit Hanein

Rabbit Models for Alzheimer's Disease

submitted by: alex01
Diana Woodruff-Pak (Temple University, Philadelphia, PA) used cholesterol-fed rabbits as a model of AD for evaluation of currently available and potential anti-Alzheimer drugs. These animals developed typical Alzheimer pathology, including behavioral changes and deposition of ß-amyloid and even tau. Galantamine and donepezil partially protected animals from Alzheimer symptomatology.

Cannabinoids

submitted by: alex01
Daniele Piomelli, PhD. - Another approach was discussed by D. Piomelli (University of California, Irvine). URB 597, an inhibitor of fatty acid amide hydrolase (FAAH), is expected to increase anandamide signaling and is being currently clinically tested in the therapy of pain. An increase in anandamide signaling may also be useful in the therapy of depression. This is a novel approach to the development of antidepressants. The signaling can be enhanced by blocking anadamide metabolism or by...

Talk by Lim

submitted by: dougramsey
Lecturer Lim leads a discussion on the Science of Learning Centers sponsored by the National Science Foundation, what they do, what are their purpose and goals, and how they are implemented in assisting a new generation of individuals expand their education and build on it.