Viewing Ensembl Regulation & ENCODE Using the Matrix

submitted by: gspudich
This tutorial demonstrates how to view sequences potentially involved in gene regulation. These sequences are analysed by Ensembl Regulation based mostly on ENCODE data, along with Roadmap Epigenomics data for human. The end of this tutorial shows how to add the full ENCODE data set to a genome display in Ensembl. The Region in Detail in the Ensembl browser will be explored. You may be interested in: Ensembl Regulation docs: http://www.ensembl.org/info/docs/func ... Region in Detail...

Eric Allen at the 2013 Genomics of Energy & Environment Meeting

submitted by: JGI

Eric Allen of Scripps and UC San Diego on "Assembly-driven metagenomics of a hypersaline microbial ecosystem" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

Systems as the Driver for Synthetic Biology

submitted by: RASEIBoulder
We now possess the ability to read and write DNA. These tools are not only revolutionizing biotechnology but also the basic life sciences as well. The challenge is that we are still learning the grammar. In other words, we often do not know which genetic perturbations to make in order to alter the behavior of an organism. As a result, synthetic biology still involves much trial and error. Moreover, we are still far from the point where we can engineer new organisms from scratch – rather,...

Looking at the Region of the LCT Gene

submitted by: gspudich
A comprehensive overview of how to use the Ensembl Region in Detail view (our main Location view) in order to view data about a genomic region. We focus on the region of the LCT gene in human. Links from this video: Video: Patches and Haplotypes in the Human Genome ( http://youtu.be/sPE9j_Hw9HU ) Video: Browsing RNA-Seq Data in Ensembl ( http://youtu.be/9NUibgdkTRY ) FAQ: What styles are available for the data tracks in views like Region in Detail?(...

Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy...

submitted by: Jamia
Full title: Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions Abstract: Objective Pharmacogenomics evaluations of variability in drug metabolic processes may be useful for making individual drug response predictions. We present an approach to deriving ‘phenotype scores’ based on existing pharmacogenomics knowledge and a patient's genomics data. Pharmacogenomics plays an important role in the bioactivation...

Scott Jordan (Physik Instrumente) at the 2012 SFAF Meeting

submitted by: JGI

Scott Jordan on "Advances in high-throughput speed, low-latency communication for embedded instrumentation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Getting leads from Big Data

submitted by: OpenHelix

This video illustrates a search of the ICGC, International Cancer Genome Consortium, for a gene lost in tumor samples. For more details see the blog post: http://blog.openhelix.eu/?p=13404

Rita Colwell (University of Maryland) at the 2012 SFAF Meeting

submitted by: JGI

Rita Colwell on "Experimental Reservoirs of Human Pathogens: The Vibrio cholerae paradigm" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Tip of the Week: Galaxy Tool Shed

submitted by: OpenHelix

Today's tip of the week is on the Galaxy Toolshed, to find more read the blog post and tip at: http://blog.openhelix.eu/?p=12988

Donna Muzny (Baylor College of Medicine) at the 2012 SFAF Meeting

submitted by: JGI

Donna Muzny on "En route to the clinic: Diagnostic sequencing applications using the Ion Torrent" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.