Description: Dr. Carl (Chip) Lavie, Professor of Medicine in the Department of Cardiovascular Diseases at the John Ochsner Heart and Vascular Institute, Ochsner Clinical School and the University of Queensland School of Medicine in New Orleans, Louisiana, discusses his article appearing as an Online First article and in the November 2011 issue of Mayo Clinic Proceedings on the effects of hyperglycemia and risk of stroke in asymptomatic men. Available at: http://tinyurl.com/6efez5x

Foam cell formation is the hallmark of early atherosclerosis. Lipid uptake by scavenger receptors (SR) in macrophages initiates chronic proinflammatory cascades linked to atherosclerosis. It has been reported that the upregulation of cholesterol efflux may be protective in the development of atherosclerosis. Ellagic acid, a polyphenolic compound mostly found in berries, walnuts, and pomegranates, possesses antioxidative, growth-inhibiting and apoptosis-promoting activities in cancer...

These powerpoint slides describe the background, objective, methods, main results, discussion, and conclusion of the article. Background: Although studies have linked vitamin D deficiency to an increased risk of cardiovascular disease (CVD), evidence regarding whether vitamin D intake from foods or supplements is prospectively associated with lower CVD risk in healthy humans is limited and inconclusive. Objective: The objective was to comprehensively evaluate the associations between...

Current dietary recommendations advise reducing the intake of saturated fatty acids (SFAs) to reduce coronary heart disease (CHD) risk, but recent findings question the role of SFAs. This expert panel reviewed the evidence and reached the following conclusions: the evidence from epidemiologic, clinical, and mechanistic studies is consistent in finding that the risk of CHD is reduced when SFAs are replaced with polyunsaturated fatty acids (PUFAs). In populations who consume a Western...

Description: Drs Marie Brown and Jennifer Bussells, practicing internists in the Chicago, Illinois area discuss their article appearing in the April 2011 issue of Mayo Clinic Proceedings. Available at: http://tinyurl.com/6ees9ar regarding patient adherence to prescribed medications.

Despite what our name might imply, the Rat Genome Database contains much more than just genomic and genetic data for the rat. This video will give you an overview of the RGD Phenotypes and Models portal—a rich resource of information on topics including animal husbandry, identifying what rat strains are good models for certain human diseases, and normal physiological measurements for a variety of rat strains.

Who knew you could find disease genes without even stepping into the laboratory? This video provides a tutorial on how to utilize the Disease Portals on the Rat Genome Database website at http://rgd.mcw.edu/wg/portals . These portals allow you to search for disease, phenotype, biological process, and pathway specific rat, mouse, and human genes and data. See our RGD website at http://rgd.mcw.edu for more information and tools for researchers...