biosights: May 12, 2014 - Phosphoinositides get cells in shape

submitted by: JCB
Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an individual, membrane-bound cell. Reversi et al. describe how the phosphoinositides PI(4,5)P2 and PI(3,4,5)P3 control the resulting cell shapes by coordinating actomyosin contractility with plasma membrane expansion. This biosights episode presents the paper by Reversi et al. from the May 12, 2014, issue of The Journal of Cell Biology and includes an interview with senior author Stefano...

Проповедь Франциска Ассизского птицам. Смысл, который придавал ей сам Святой и восприятие ее современниками (на основе письменных источников XIII века и ранней иконографии этой проповеди XIII-XV веков).

submitted by: khlopov55
Костыря Виктория Александровна Исследовательская работа на тему: Проповедь Франциска Ассизского птицам. Смысл, который придавал ей сам Святой и восприятие ее современниками (на основе письменных источников XIII века и ранней иконографии этой проповеди XIII-XV веков)....

biosights: April 14, 2014 - An actin lever flattens out the cell

submitted by: JCB
The lamella is a broad, flat region that forms at the front of migrating cells and adheres to the underlying substrate. Burnette et al. reveal that cells flatten out the lamella by mechanically coupling a contractile actomyosin network at the dorsal surface to ventral cell adhesions. This biosights episode presents the paper by Burnette et al. from the April 14, 2014, issue of The Journal of Cell Biology and includes an interview with authors Dylan Burnette (Vanderbilt University School of...

Can you still exercise when you have cancer?

submitted by: mdanderson
Is it safe to exercise when you have cancer? Are there specific exercises that should be avoided or are there warning signs to stop your workout? Whether you’re an athlete or have never exercised, this advice is for the cancer patient/survivor who wants to increase longevity through exercise. Carol Harrison, senior exercise physiology technologist at MD Anderson Cancer Center, offers suggestions and shares information to help cancer survivors stay on track with their exercise programs.

biosights: March 17, 2014 - Blebs lead the way in Dictyostelium chemotaxis

submitted by: JCB
Membrane blebs can help the leading edge of migrating cells protrude forwards, but the contribution of blebs to the motility of Dictyostelium cells is unclear. Zatulovskiy et al. reveal that blebs form at the front of chemotaxing Dictyostelium cells, particularly when the cells are faced with a mechanically resistant environment, and that this process is guided by a PI3-kinase-dependent signaling pathway. This biosights episode presents the paper by Zatulovskiy et al. from the March 17,...

Effects of Periodontal Treatment on Lung Function and Exacerbation Frequency in Patients with Chronic Obstructive Pulmonary Disease and Chronic Periodontitis: A 2-Year Pilot Randomized Controlled Trial

submitted by: xuanzhou
Abstract AIM: To evaluate the direct effects of periodontal therapy in Chronic Obstructive Pulmonary Disease (COPD) patients with chronic periodontitis (CP). MATERIALS AND METHODS: In a pilot randomized controlled trial, 60 COPD patients with CP were randomly assigned to receive scaling and root planing (SRP) treatment, supragingival scaling treatment, or oral hygiene instructions only with no periodontal treatment. We evaluated their periodontal indexes, respiratory function and COPD...
Authors: Xuan Zhou, Jing Han, Zhiqiang Liu, Yiqing Song, Zuomin Wang, Zheng Sun