When leukocytes enter or exit the blood stream, they leave small wounds both in and between the vascular endothelial cells, which must be quickly repaired so that the endothelium can maintain its barrier function. Martinelli et al. reveal that wounding causes a loss of tension in endothelial cells, inducing the formation of ventral lamellipodia that close the holes left by transmigrating leukocytes. This biosights episode presents the paper by Martinelli et al. from the April 29, 2013, issue...

Most dividing cells possess a spindle assembly checkpoint that prevents them from entering anaphase until all their chromosomes are correctly attached to the metaphase spindle. Shao et al. reveal that Xenopus eggs lack this checkpoint, allowing them to undergo meiosis in the absence of microtubules or in the presence of monopolar spindles. This biosights episode presents the paper by Shao et al. from the April 15, 2013 issue of The Journal of Cell Biology and includes an interview with...

Documentation of the UPLB Centennial Professorial Chair Lecture on "Hotbed of Confusion: Tenure Systems in the Uplands" by Professor Rolando T. Bello, Assistant Professor, College of Public Affairs and Development, UPLB, at CPAf Rooms 303-304 on April 15, 2013.

Background: Periodontal disease and diabetes mellitus are common, chronic diseases worldwide. Epidemiologic and biologic evidence suggests periodontal disease may affect diabetes. Objective: To systematically review non-experimental, epidemiologic evidence for effects of periodontal disease on diabetes control, complications, and incidence. Data sources: Electronic bibliographic databases, supplemented by hand searches of recent and future issues of relevant journals. Study eligibility...

Documentation of the special lecture on "From Block Codes to Convolutional Codes, Subspace Codes and Grassmannians" by Dr. Virgilio P. Sison, Director of the Institute of Mathematical Science and Physics, College of Arts and Science, UPLB last March 21, 2013 at the Mathematics Building, UPLB, College, Laguna. In his talk, constructions of distance-optimal systematic unit-memory convolutional codes from linear block codes over finite semi-local rings were discussed. Secondly, the...

During the first meiotic division of mammalian oocytes, the meiotic spindle and chromosomes move from the interior to the periphery of the cell. Yi et al. reveal that chromosome migration occurs in two sequential phases driven by the actin nucleators Fmn2 and the Arp2/3 complex. This biosights episode presents the paper by Yi et al. from the March 4, 2013, issue of The Journal of Cell Biology and includes an interview with senior author Rong Li (Stowers Institute for Medical Research, Kansas...