biosights: May 13, 2013 - Ventral lamellipodia plug the gaps

submitted by: JCB
When leukocytes enter or exit the blood stream, they leave small wounds both in and between the vascular endothelial cells, which must be quickly repaired so that the endothelium can maintain its barrier function. Martinelli et al. reveal that wounding causes a loss of tension in endothelial cells, inducing the formation of ventral lamellipodia that close the holes left by transmigrating leukocytes. This biosights episode presents the paper by Martinelli et al. from the April 29, 2013, issue...

Bacterial Aerotaxis

submitted by: mhrussel

Aerotaxis is the movement of an organism in response to environmental oxygen concentrations, either towards or away from a given oxygen concentration. Many bacteria are microaerophilic meaning they prefer environments with low oxygen content. Higher or lower O2 content than the optimum are considered a repellant and bacteria will navigate towards the optimum. This animation is an overview of studying aerotaxis in motile bacteria.

Glycolysis animation

submitted by: mhrussel

Glycolysis is a determined sequence of ten reactions involving ten intermediate compounds (one of the steps involves two intermediates). The intermediates provide entry points to glycolysis. This animation features the 3D protein structures of all ten enzymes as well as the enzyme substrate and products.

Weight loss, weight maintenance, and adaptive thermogenesis

submitted by: stefancamps
Background: Diet-induced weight loss is accompanied by adaptive thermogenesis, ie, a disproportional or greater than expected reduction of resting metabolic rate (RMR). Objective: The aim of this study was to investigate whether adaptive thermogenesis is sustained during weight maintenance after weight loss. Design: Subjects were 22 men and 69 women [mean 6 SD age: 40 6 9 y; body mass index (BMI; in kg/m2): 31.9 6 3.0]. They followed a very-low-energy diet for 8 wk, followed by a...
Authors: Stefan Camps, Sanne Verhoef, Klaas Westerterp

Jose Pruneda-Paz at the 2013 Genomics of Energy & Environment Meeting

submitted by: JGI

Jose Pruneda-Paz of UC San Diego on "Uncovering Transcriptional Circuits in Arabidopsis by Functional Genomics" at the 8th Annual Genomics of Energy & Environment Meeting in Walnut Creek, Calif.

Rick Amasino at the 2013 Genomics of Energy & Environment Meeting

submitted by: JGI

Rick Amasino of the University of Wisconsin on "Regulation of Flowering in Brachypodium distachyon" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.