biosights: November 25, 2013 - Caspases work as branch managers

submitted by: JCB
When a growing axon nears its target, it arborizes, or branches, to form numerous synaptic connections. Campbell and Okamoto reveal that localized caspase activation downstream of Slit-Robo signaling promotes arbor dynamics and restricts arbor growth. This biosights episode presents the paper by Campbell and Okamoto from the November 25, 2013, issue of The Journal of Cell Biology and includes an interview with lead author Douglas Campbell (formerly at the RIKEN Brain Science Institute,...

MWV #81 - Sheldon Campbell - The Singing Microbiologist

submitted by: MicrobeWorld
Sheldon Campbell sings about microbiology. Dr. Campbell teaches microbiology at Yale School of Medicine and he uses music to enhance his lectures. He has one song for every block of lectures he gives on a major topic. Songs he's written include a song about fungi, tick borne disease, tuberculosis and one that reviews all of microbiology in eight minutes. Dr. Campbell hasn't done any testing to see his songs are more effective at getting his message across but he does get the occasional...

Extraction sockets: erratic healing impeding factors

submitted by: freetist
Aim: The aim of this exploratory study was to analyse prevalence of extraction sockets showing erratic healing and evaluate factors potentially impeding healing. Methods: Erratic healing was defined as extraction sites showing clinical observations of fibrous scar tissue occupying the extraction site rather than bone following 12 or more weeks of healing. Computerized tomography was used to evaluate characteristics and calculate Hounsfield unit scores for sites showing erratic healing....
Authors: Jung-Hoon Kim, Cristiano Susin, Jeong-Hyun Min, Hee-Yeon Suh, Eun-Jung Sang, Young Ku, Ulf M. E. Wikesjo, Ki-Tae Koo

biosights: October 28, 2013 - A framework for understanding muscle microtubules

submitted by: JCB
The microtubules of skeletal muscle fibers are arranged into an orthogonal grid, but how this network is formed is unknown. Oddoux et al. reveal that the network is built by dynamic microtubules nucleated from Golgi elements. This biosights episode presents the paper by Oddoux et al. from the October 28, 2013, issue of The Journal of Cell Biology and includes an interview with senior author Evelyn Ralston (NIH, Bethesda, MD). Produced by Caitlin Sedwick and Ben Short. See the associated...

biosights: September 30, 2013 - The nodal network

submitted by: JCB
In addition to specialized actin structures such as lamellipodia and stress fibers, cells are thought to contain a contractile actomyosin matrix that maintains cell shape. Luo et al. describe the organization and dynamics of an actomyosin network that may fulfill this function. This network is formed by actin nodes that contain the formin DAAM1 and the crosslinker filamin A, and that are connected to each other by myosin II. This biosights episode presents the paper by Luo et al. from the...

The Nature Explorers Chiricahua Part 12 of 12

submitted by: thenatureexplorers

Chiricahua is a "Sky Island" region that supports a variety of wildlife, some of which are more commonly thought of as denizens of subtropical habitats in Mexico or Central America. Even in February with snow and temperatures as low as -10°F we still found a cornucopia of nature, turkeys, woodpeckers, centipedes, pines, yuccas, agaves, and more.