biosights: June 9, 2014 - Rab18 tilts the balance of ER structure

submitted by: JCB
The endoplasmic reticulum consists of peripheral tubular networks connected to sheet-like domains surrounding the nucleus. Gerondopoulos et al. reveal that the Rab3GAP complex, which is mutated in the neurodevelopmental disorder Warburg Micro Syndrome, is a guanine nucleotide exchange factor that activates the small GTPase Rab18 (also mutated in Warburg Micro Syndrome) to control the balance between ER tubules and sheets. This biosights episode presents the paper by Gerondopoulos et al. from...

Paraplegic will walk again wearing exoskeleton at the World Cup

submitted by: nsf

Built with funding for basic research from the National Science Foundation, Dr. Miguel Nicolelis and the Walk Again Project have built an exoskeleton that will allow paraplegics to walk again. The exoskeleton uses computer algorithms to interpret the user's brain activity, which powers the exoskeleton forward.

biosights: May 12, 2014 - Phosphoinositides get cells in shape

submitted by: JCB
Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an individual, membrane-bound cell. Reversi et al. describe how the phosphoinositides PI(4,5)P2 and PI(3,4,5)P3 control the resulting cell shapes by coordinating actomyosin contractility with plasma membrane expansion. This biosights episode presents the paper by Reversi et al. from the May 12, 2014, issue of The Journal of Cell Biology and includes an interview with senior author Stefano...

Dan Voytas at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI

Dan Voytas, University of Minnesota, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

David Berry at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI

David Berry, University of Vienna, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Itai Sharon at the 2014 DOE JGI Genomics of Energy & Environment Meeting

submitted by: JGI

Itai Sharon, UC Berkeley, at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.