JCB's videos (71)


488
Oct 28, 2013
biosights: October 28, 2013 - A framework for understanding muscle microtubules

The microtubules of skeletal muscle fibers are arranged into an orthogonal grid, but how this network is formed is...

509
Sep 30, 2013
biosights: September 30, 2013 - The nodal network

In addition to specialized actin structures such as lamellipodia and stress fibers, cells are thought to contain a...

781
Sep 3, 2013
biosights: September 2, 2013 - Shrinking microtubules pull the centrosome...

When a T cell encounters a target antigen-presenting cell, it moves its centrosome to the immunological synapse that...

455
Aug 6, 2013
biosights: August 5, 2013 - Epithelia restored by healing waves

Epithelial cells around the edge of a wound assemble an actomyosin cable that constricts to draw the wound closed,...

460
Jul 16, 2013
biosights: July 8, 2013 - Vinculin delivers a clutch performance

At the leading edge of migrating cells, actin assembly and membrane protrusion are closely coupled with the formation...

574
Jun 11, 2013
biosights: June 10, 2013 - Netrin Throws Anchor Cells into the Breach

Cell invasion through basement membranes is crucial for both normal development and cancer metastasis but relatively...

901
May 15, 2013
biosights: May 13, 2013 - Ventral lamellipodia plug the gaps

When leukocytes enter or exit the blood stream, they leave small wounds both in and between the vascular endothelial...

476
Apr 17, 2013
biosights: April 15, 2013 - Frog oocytes evade the checkpoint

Most dividing cells possess a spindle assembly checkpoint that prevents them from entering anaphase until all their...

696
Mar 21, 2013
biosights: March 18, 2013 - Breaking egg symmetry

During the first meiotic division of mammalian oocytes, the meiotic spindle and chromosomes move from the interior to...

499
Feb 21, 2013
biosights: February 18, 2013 - Erecting a myosin scaffold for cytokinesis

Cell division requires the coordinated action of proteins that promote actomyosin contraction, membrane trafficking,...

514
Jan 28, 2013
biosights: January 21, 2013 - How cell shape changes unfold

Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al....

504
Jan 4, 2013
biosights: Decemeber 24, 2012 - Global sourcing for cytokinetic ring assembly

At the end of cytokinesis, the microtubule-rich midbody connecting the daughter cells is either shed into the...

421
Nov 27, 2012
biosights: November 26, 2012 - Global sourcing for cytokinetic ring assembly

Fission yeast are thought to assemble their cytokinetic actomyosin rings from actin filaments nucleated at...

574
Nov 12, 2012
biosights: October 29, 2012 - A stiff test for collectively migrating cells

The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but...