JCB's videos (66)


541
Jun 11, 2013
biosights: June 10, 2013 - Netrin Throws Anchor Cells into the Breach

Cell invasion through basement membranes is crucial for both normal development and cancer metastasis but relatively...

852
May 15, 2013
biosights: May 13, 2013 - Ventral lamellipodia plug the gaps

When leukocytes enter or exit the blood stream, they leave small wounds both in and between the vascular endothelial...

450
Apr 17, 2013
biosights: April 15, 2013 - Frog oocytes evade the checkpoint

Most dividing cells possess a spindle assembly checkpoint that prevents them from entering anaphase until all their...

666
Mar 21, 2013
biosights: March 18, 2013 - Breaking egg symmetry

During the first meiotic division of mammalian oocytes, the meiotic spindle and chromosomes move from the interior to...

457
Feb 21, 2013
biosights: February 18, 2013 - Erecting a myosin scaffold for cytokinesis

Cell division requires the coordinated action of proteins that promote actomyosin contraction, membrane trafficking,...

479
Jan 28, 2013
biosights: January 21, 2013 - How cell shape changes unfold

Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al....

475
Jan 4, 2013
biosights: Decemeber 24, 2012 - Global sourcing for cytokinetic ring assembly

At the end of cytokinesis, the microtubule-rich midbody connecting the daughter cells is either shed into the...

363
Nov 27, 2012
biosights: November 26, 2012 - Global sourcing for cytokinetic ring assembly

Fission yeast are thought to assemble their cytokinetic actomyosin rings from actin filaments nucleated at...

509
Nov 12, 2012
biosights: October 29, 2012 - A stiff test for collectively migrating cells

The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but...

508
Oct 1, 2012
biosights: October 1, 2012 - Cortical dynein puts the spindle in its place

The position of the mitotic spindle is controlled by the microtubule-based motor dynein and a ternary complex of the...

493
Aug 8, 2012
biosights: August 6, 2012 - Redistribution aids the pore

In animal cells, the nuclear lamina keeps nuclear pore complexes evenly distributed throughout the nuclear envelope....

473
Jul 9, 2012
Asters help embryonic nuclei find their own space

In early Drosophila embryos, nuclei undergo rapid, synchronous divisions without being separated into individual...

373
Jun 12, 2012
T cell signaling goes with the flow

Activated T cell receptors stimulate actin polymerization at the periphery of the immunological synapses that form...

513
May 14, 2012
A new way forward for fibroblasts

Fibroblasts moving across two-dimensional surfaces form lamellipodial protrusions at their leading edge, but how...