Evaluating the Patient with Diarrhea: A Case-Based Approach

submitted by: WentzMR

Dr. Seth Sweetser, Assistant Professor of Medicine in the Division of Gastroenterology and Hepatology at Mayo Clinic in Rochester, MN, discusses his article appearing in the June 2012 issue of Mayo Clinic Proceedings where he shares a 5 step approach for assessing diarrhea in patients and shares 3 cases demonstrating the practical applications of the evaluation. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00382-5/fulltext

Statins in heart failure: The paradox between large randomized clinical trials and real life.

submitted by: WentzMR
Dr. Paloma Gastelurrutia, a researcher at Germans Trias i Pujol Health Research Institute, in Barcelona, Spain, discusses her article appearing in the June 2012 issue of Mayo Clinic Proceedings, which compares the results of clinical trial studies and long term follow-up with real-life cohorts of patients using statins. Large clinical trials did not show success with statins, but cohort studies revealed more optimistic results. Available at:...

The Limits of Acceptable Biological Variation in Elite Athletes: Should Sex Ambiguity Be Treated Differently from Other Advantag

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Dr. J. Michael Bostwick, Professor of Psychiatry at Mayo Clinic in Rochester, MN, discusses his article appearing in the June 2012 issue of Mayo Clinic Proceedings, where he explores sex, gender, and other genetic traits in elite athletes. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00439-9/fulltext

Use of Nonclonal Serum Immunoglobulin Free Light Chains to Predict Overall Survival in the General Population.

submitted by: WentzMR

Dr. S. Vincent Rajkumar, Professor of Medicine in the Division of Hematology at Mayo Clinic in Rochester, MN, illuminates the results an article appearing in the June 2012 issue of Mayo Clinic Proceedings of an Olmsted County population- based study where detection of high polyclonal free light chain levels can predict mortality outcomes across multiple conditions. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00388-6 /fulltext

The Obesity Paradox, Cardiorespiratory Fitness, and Coronary Heart Disease

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Dr. Carl (Chip) Lavie, a cardiologist from Ochsner Clinic in New Orleans, LA, discusses an article appearing in the May 2012 issue of Mayo Clinic Proceedings, which provides further evidence for the validation of the obesity paradox. Previous study results may be misleading if fitnessof the patient is not also considered.
Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00266-2/fulltext

Dr. Thomas Gerber discusses the articles featured on the cover page of the May 2012

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Dr. Thomas Gerber, Associate Editor for Mayo Clinic Proceedings, discusses the articles featured on the cover page of the May 2012 issue. These include: •Relationship of Zolpidem and Cancer Risk: A Taiwanese Population-Based Cohort Study, by Dr. Chia Hung Kao and colleagues; and its accompanying editorial, Insomnia, Hypnotic Drug Use, and Patient Well-being: First, Do No Harm, by Dr. Barbara Phillips •Anthropometric Correlates of Total Body Fat, Abdominal Adiposity, and...

Computer Activities, Physical Exercise, Aging, and Mild Cognitive Impairment:

submitted by: WentzMR
Dr. Yonas Geda, a physician scientist at Mayo Clinic in Scottsdale, Arizona, USA, discusses his article appearing in the May 2012 issue of Mayo Clinic Proceedings. The study shows a synergistic interaction between computer use and moderate physical exercise in being associated with a decreased odds of having mild cognitive impairment, the intermediate stage between normal aging and dementia. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00304-7/fulltext

Common Musculoskeletal Tumors of Childhood and Adolescence

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Dr. Carola Arndt, a pediatric hematologist from Mayo Clinic in Rochester, MN, discusses her article appearing in the May 2012 issue of Mayo Clinic Proceedings, and reviews the diagnosis, prognosis, staging, multidisciplinary therapy, new directions in therapy,
and long-term complications of treatment for common childhood tumors. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00301-1/fulltext

Ten Recommendations for Closing the Credibility Gap in Reporting

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Dr. Daniel Haller and Bernadette Mansi describe results of an article appearing in the May 2012 issue of Mayo Clinic Proceedings detailing a collaboration between industry representatives and medical journal editors to characterize the credibility gap in reporting industry-sponsored research and identify potential approaches to resolve it. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00298-4/fulltext

Meta-analysis of Vancomycin for the Treatment of Patients

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Dr. Konstantinos Vardakas, Internal Medicine physician from Alfa Institute of Biomedical Sciences, in Athens, Greece, reviews his article appearing in the April 2012 issue of Mayo Clinic Proceedings, which compares the effectiveness of vancomycin and other antibiotics in treating patients with gram-positive infections. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(12)00208-X/fulltext