Video Tip of the Week: New Genetic Testing Registry (GTR) Resource

submitted by: OpenHelix

For more information, see our blog post at http://blog.openhelix.eu/?p=11439. In this movie we compare the new GTR resource from NCBI to other clinical resources that you may already be using, to answer why you may want to use the GTR.

ADHD After Early Exposure to General Anesthesia and Surgery

submitted by: WentzMR

Dr. David Warner, Professor of Anesthesiology at Mayo Clinic in Rochester, MN, discusses his article appearing in the February 2012 issue of Mayo Clinic Proceedings revealing an association between ADHD ) and exposure to multiple procedures and surgery requiring general anesthesia in young children. Available at:
http://www.mayoclinicproceedings.org/article/S0025-6196(11)00072-3/fulltext

Deep Brain Stimulation in Tourette Syndrome: A Description of 3 Patients With Excellent Outcome.

submitted by: WentzMR

Dr. Rodolfo Savica, Neurologist at Mayo Clinic in Rochester, MN, discusses his article appearing in the January 2012 issue of Mayo Clinic Proceedings showcasing 3 highly successful outcomes in patients with Tourette syndrome who underwent deep brain stimulation. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(11)00012-7/fulltext

Cheaper, Simpler, and Better: Tips for Treating Seniors With Parkinson Disease

submitted by: WentzMR
Dr. J. Eric Ahlskog, a Consultant in the Department of Neurology at Mayo Clinic in Rochester, MN, discusses his article appearing in the December 2011 issue of Mayo Clinic Proceedings on the effectiveness of treating Parkinson's Disease with carbidopa/levodopa and notes its most effective dosage regimen is tailored to the needs of the patient. Available at: http://www.mayoclinicproceedings.com/content/86/12/1211.full

Epizyme - HMT "Tree" Presentation Video

submitted by: Epizyme
A survey of the human genome was performed to understand the constituency of protein methyltransferases (both protein arginine and lysine methyltransferases) and the relatedness of their catalytic domains. We identified 51 protein lysine methyltransferase proteins based on similarity to the canonical Drosophila Su(var)3-9, enhancer of zeste (E(z)), and trithorax (trx) domain. Disruptor of telomeric silencing-1-like, a known protein lysine methyltransferase, did not fit within the protein...
Authors: Christopher Sneeringer, Margaret Scott, Keith Elliston, Danielle Johnston, Lei Jin, L. fred Jerva, Victoria Richon, Robert Copeland, Christina Majer

Clinical and Radiologic Correlations of Central Pontine Myelinolysis Syndrome

submitted by: mcgheekkm
Dr. Jonathan Graff-Radford from the Neurology Department at Mayo Clinic in Rochester, MN, discusses his article appearing as an Online First article and in the print issue of the November 2011 issue of Mayo Clinic Proceedings on radiologic findings of Central Pontine Myelinolysis Syndrome and their correlation to clinical outcomes. Available at: http://mayoclinicproceedings.com/content/early/recent