Sitting-Time, Physical Activity, and Depressive Symptoms in Mid-Aged Women

submitted by: jannique.van.uffelen
Background: Associations of sitting-time and physical activity with depression are unclear. Purpose: To examine concurrent and prospective associations between both sitting-time and physical activity with prevalent depressive symptoms in mid-aged Australian women. Methods: Data were from 8950 women, aged 50–55 years in 2001, who completed mail surveys in 2001, 2004, 2007, and 2010. Depressive symptoms were assessed using the Center for Epidemiological Studies Depression questionnaire....
Authors: Jannique van Uffelen, Yolanda van Gellecum, Nicola Burton, Geeske Peeters, Kristiann Heesch, Wendy Brown

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women

submitted by: enphpdom
Background: Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have been observed in offspring whose mothers were exposed to famine or who conceived in the Gambian rainy season. Objective: The objective was to understand the seasonality of DNA methylation patterns in rural Gambian women. We studied natural...
Authors: P Dominguez-Salas, AM Prentice

Fruit, Mediterranean-style, and high-fat and -sugar diets are associated with the risk of night sweats and hot flushes in midlife

submitted by: gcmherber
Background: Diet has been suggested to be a potential risk factor for vasomotor menopausal symptoms (VMS), i.e. hot flushes and night sweats. Objective: We investigated the associations between dietary patterns and risk of VMS using data from mid-aged women born between 1946 and 1951 in the Australian Longitudinal Study on Women’s Health. Design: A prospective cohort study of 6,040 women with a natural menopause, who were followed up at three-year intervals over nine years. Dietary...
Authors: GCM Herber-Gast

Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studies

submitted by: Geoffrey Livesey
Background: Although much is known about the association between dietary glycemic load (GL) and type 2 diabetes (T2D), prospective cohort studies have not consistently shown a positive dose-response relation. Objective: We performed a comprehensive examination of evidence on the dose response that links GL to T2D and sources of heterogeneity among all prospective cohort studies on healthy adults available in the literature. Design: We conducted a systematic review of all prospective...
Authors: Geoffrey Livesey, Richard Taylor, Helen Livesey, Simin Liu

UT MD Anderson Cancer Center launches unprecedented Moon Shots Program to increase patient survival during the next decade

submitted by: mdanderson
Inspired by America’s drive a generation ago to put a man on the moon, MD Anderson’s Moon Shots Program is a highly-concentrated effort to rapidly and dramatically decrease suffering and death in several major cancers, including acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS); chronic lymphocytic leukemia (CLL); lung; melanoma; prostate and two cancers linked at the molecular level: triple-negative breast and ovarian. Focused teams are building on new technology and...

Association between oral bisphosphonate use and dental implant failure among middle-aged women

submitted by: lborrell
AIM: To investigate the association between the use of oral bisphosphonate therapy and dental implant failure. MATERIALS AND METHODS: The case-control study involved 337 female patients, aged 40 years and older, who had 1181 implants placed at the Department of Periodontology and Implant Dentistry at New York University College of Dentistry between January 1997 and December 2004. Cases, defined as women with one or more implant failures, were identified from the departmental database....
Authors: Julie Yip, Luisa Borrell

Retinol May Counteract the Negative Effect of Cadmium on Bone

submitted by: agnake
Cadmium and high vitamin A intake are both proposed risk factors for low bone mineral density (BMD), but potential interactions have not been studied. Within the Women’s Health in the Lund Area, a population-based study in southern Sweden,wemeasured retinol in serumamong 606womenaged 54–64 y. Data onBMDwere measured byDXAat the distal forearm. Parathyroid hormone (PTH), bone alkaline phosphatase (bALP), and osteocalcin in serum and deoxypyridinoline (DPD) and cadmium in urine were...
Authors: Thomas Lundh, Jonas Lidfeldt, Per Bjellerup, Staffan Skerfving, Helen Håkansson, Annette Engström, Göran Samsioe, Marie Vahter, Agneta Åkesson

Vitamin D intake and risk of cardiovascular disease in US men and women

submitted by: qisun
These powerpoint slides describe the background, objective, methods, main results, discussion, and conclusion of the article. Background: Although studies have linked vitamin D deficiency to an increased risk of cardiovascular disease (CVD), evidence regarding whether vitamin D intake from foods or supplements is prospectively associated with lower CVD risk in healthy humans is limited and inconclusive. Objective: The objective was to comprehensively evaluate the associations between...
Authors: Joann Manson, Frank Hu, Edward Giovanucci, Eric Rimm, Ling Shi, Qi Sun, Kathryn Rexrode

Women In Bioinformatics Seminar Series Documentary Trailer

submitted by: WomenInBioinformatics

A series of speakers sharing their ground breaking science and their journeys as women in a predominantly male subject area.

Do You Think You Want to Be a Scientist? Comments from Women in Bioinformatics for High School Students

submitted by: WomenInBioinformatics

A series of speakers sharing their ground breaking science and their journeys as women in a predominantly male subject area. Do You Think You Want to Be a Scientist? Comments from Women in Bioinformatics for High School Students