First-year progress in MD Anderson’s Moon Shots Program

submitted by: mdanderson
The University of Texas MD Anderson Cancer Center in September 2012 announced its Moon Shots Program, an unprecedented effort to dramatically accelerate the pace of converting scientific discoveries into clinical advances that reduce cancer deaths. The program initially targets acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS); chronic lymphocytic leukemia (CLL); lung cancer; melanoma; prostate cancer; and triple-negative breast and high-grade serious ovarian cancers....

Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis

submitted by: arup.indra
Keratinocytes contribute to melanocyte activity by influencing their microenvironment, in part, through secretion of paracrine factors. Here we discovered that p53 directly regulates Edn1 expression in epidermal keratinocytes and controls UV-induced melanocyte homeostasis. Selective ablation of EDN1 in murine epidermis (EDN1ep-/-) does not alter melanocyte homeostasis in newborn skin but decreases dermal melanocytes in adult skin. Results showed that keratinocytic EDN1 in a non-cell...
Authors: Daniel J. Coleman, Gitali Ganguli-Indra, Stephen Hyter, Arup Indra, Steven Ma, Gary F. Merrill, Masashi Yanagisawa

Tips to Help Kids Avoid Adult Cancers

submitted by: mdanderson

Beverly Gor, Ed.D., postdoctoral fellow in the Center for Health Equity and Evaluation Research at The University of Texas MD Anderson Cancer Center, discusses healthy lifestyle choices you can make for your children to help prevent the development of certain adult cancers; such as prostate, breast and colon. Gor stresses the importance of healthy nutrition and exercise to reduce the risk of developing cancer later in life.

Skin Cancer of the Eye – Uveal Melanoma

submitted by: mdanderson

Uveal melanoma is a very rare cancer that forms on the eye’s skin tissue, usually in the back part of the eye under the retina (choroid). Sapna Patel, M.D., Assistant Professor in the Department of Melanoma Medical Oncology at The University of Texas MD Anderson Cancer Center, discusses the causes, symptoms and treatment of uveal melanoma. Patel also explains why it is important for everyone to have their eyes examined, even if your vision is 20/20.

The deceptive nature of UVA-tanning versus the modest protective effects of UVB-tanning on human skin

submitted by: vhearing
The relationship between human skin pigmentation and protection from ultraviolet (UV) radiation is an important element underlying differences in skin carcinogenesis rates. The association between UV damage and the risk of skin cancer is clear, yet a strategic balance in exposure to UV needs to be met. Dark skin is protected from UV-induced DNA damage significantly more than light skin due to the constitutively higher pigmentation but an as yet unresolved and important question is what...
Authors: Vincent j. Hearing, Ludger Kolbe, Yoshinori Miyamura, Sergio g. Coelho, Kathrin Schlenz, Jan Batzer, Christoph Smuda, Wonseon Choi, Michaela Brenner, Thierry Passeron, Guofeng Zhang, Rainer Wolber

Dr Wetter discusses Feb 2010 Mayo Clinic Proceedings article on Stevens-Johnson syndrome

submitted by: mcgheekkm

Dr. Wetter, Mayo Clinic dermatologist, discusses various features of Stevens-Johnson syndrome based on an article published in the February 2010 issue of Mayo Clinic Proceedings.

La Vitamina D (Vitamin D) "Leyendo Entre Los Genes" ("Reading Between the Genes")

submitted by: clownfish

Este video describe la deficiencia de vitamina D y el proceso de adaptación a latitudes del norte.

Diversity Profile of the Human Skin Microbiome in Health and Disease Elizabeth A. Grice, National Institutes of Health

submitted by: dougramsey

Elizabeth A. Grice of National Institutes of Health discusses "Diversity Profile of the Human Skin Microbiome in Health and Disease"

New Skin - Partners Video Magazine

submitted by: csrees

Scientists in Illinois are using corn protein to create new skin and deliver medicine through nanotubes. New Skin is a segment from Partners Video Magazine's latest episode, The Science of Small. To view the entire episode visit: http://www.csrees.usda.gov/newsroom/partners/partners.html

XERODERMA PIGMENTOSUM

submitted by: camdic
Hereditary disease, trasmitted with recessive autosomical modality, the XP is characterized from extreme photosensivity, that causes strict and premature damages to level of the cutis and of the eyes. Its incidence is of 1: 250 thousand in Europe and USA, while in Japan the relationship is of 1:40 thousand. In the child affected by XP, also short exposure to the sun's ultraviolet rays, determines severe cutaneous sunburn with slow resolution, therefore it is from avoiding sources of...