protein structure

This is a podcast and slides of a lecture given on Nov 02, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers some aspects of protein ligand interactions with emphasis on SMAP for determining similar ligand binding sites and the pharmacological implications.

This is a podcast and slides of a lecture given on Nov 16, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers determining domains from 3D protein structure.

This is a podcast and slides of a lecture given on Nov 9, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Michael Gilson. It covers structure and ligand based structure methods used in drug discovery.

Course: Computational Systems Biology Title: Further Properties of Complex (Biological) Networks Speaker: Arthur Dong Date: 20111110

For more information about this resource, please see our blog post at URL http://blog.openhelix.eu/?p=9933. In this tip I introduce users to the VnD, or genetic Variation and Drug database from the Korean Bioinformation Center, or KOBIC.

For more information on this resource see our blog post at http://blog.openhelix.eu/?p=8838. In the tip I use the myosin VI structure summary page from NCBI's Molecular Modeling Database (MMDB) as my example of how to use the updated version of the Cn3D interactive 3D viewer from NCBI.

This is a Podcast from the University of California San Diego Graduate Student Bioinformatics I class Lecture 10 for 2010. Using Protein Structure to Study Evolution. See http://www.sdsc.edu/pb/edu/pharm201/ for details. Traditionally protein structure has been studied through looking at evolution. Most recently evolution has been studied through looking at protein structure. Goal: Provide an appreciation of what protein structure brings to the study of evolution. Reading: Chapter 23 of...

This is two posters given together relating to molecular visualization.

Plaque formation in Alzheimer's Disease (AD) is seeded by excision products of Amyloid precursor protein (APP) generated by the combined activities of beta and gamma secretases. To reduce the production of these neurotoxic peptides the inhibition of beta-secretase (Beta-site APP Cleaving Enzyme, BACE1, Swiss-Prot P56817) is being intensively pursued as a possible therapy for AD and all drug candidates are screened for selectivity against the paralogue (BACE2, Swiss-Prot Q9Y5Z0) which...

Protein functional prediction