Video Tip of the Week: The PSI SBKB's New Content Hubs

submitted by: OpenHelix
For more information about this resource, see our blog post at URL: http://blog.openhelix.com/?p=12634 In the tip I will feature the newly organized content hubs over at the Protein Structure Initiative's Structural Biology Knowledgebase, or PSI SBKB. These scientific hubs, organized by content, make it easy for users to access specific content offered by both the SBKB and the PSI as a whole.

UCSD Phar201 Protein Ligand Interactions

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 02, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers some aspects of protein ligand interactions with emphasis on SMAP for determining similar ligand binding sites and the pharmacological implications.

UCSD Phar201 Structural Domains in Proteins

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 16, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers determining domains from 3D protein structure.

UCSD Phar201 Chemical Data and Computer-Aided Drug Discovery

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 9, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Michael Gilson. It covers structure and ligand based structure methods used in drug discovery.

20111110 - Computational Systems Biology - Further Properties of Complex (Biological) Networks

submitted by: rostlab

Course: Computational Systems Biology
Title: Further Properties of Complex (Biological) Networks
Speaker: Arthur Dong
Date: 20111110

Tip of the Week: VnD Resource for Genetic Variation and Drug Information

submitted by: OpenHelix

For more information about this resource, please see our blog post at URL http://blog.openhelix.eu/?p=9933. In this tip I introduce users to the VnD, or genetic Variation and Drug database from the Korean Bioinformation Center, or KOBIC.

Tip of the Week: Update to NCBI's Cn3D Viewer

submitted by: OpenHelix

For more information on this resource see our blog post at http://blog.openhelix.eu/?p=8838. In the tip I use the myosin VI structure summary page from NCBI's Molecular Modeling Database (MMDB) as my example of how to use the updated version of the Cn3D interactive 3D viewer from NCBI.

Structural Bioinformatics Pharm 201 UCSD Lecture 10 2010

submitted by: Phil
This is a Podcast from the University of California San Diego Graduate Student Bioinformatics I class Lecture 10 for 2010. Using Protein Structure to Study Evolution. See http://www.sdsc.edu/pb/edu/pharm201/ for details. Traditionally protein structure has been studied through looking at evolution. Most recently evolution has been studied through looking at protein structure. Goal: Provide an appreciation of what protein structure brings to the study of evolution. Reading: Chapter 23 of...

Real-time Ray Tracing of Complex Molecular Scenes with BALLView and RTfact

submitted by: akdehof

This is two posters given together relating to molecular visualization.

The Evolution of Beta Amyloid Cleaving Enzyme (BACE1): an Alzheimer’s Disease Drug Target

submitted by: cdsouthan
Plaque formation in Alzheimer's Disease (AD) is seeded by excision products of Amyloid precursor protein (APP) generated by the combined activities of beta and gamma secretases. To reduce the production of these neurotoxic peptides the inhibition of beta-secretase (Beta-site APP Cleaving Enzyme, BACE1, Swiss-Prot P56817) is being intensively pursued as a possible therapy for AD and all drug candidates are screened for selectivity against the paralogue (BACE2, Swiss-Prot Q9Y5Z0) which...