BindingDB: Find and view all data for a target of interest

submitted by: gnicpro

This tutorial describes how to view all published binding data for a protein target in BindingDB
http://bindingdb.org

UCSD Phar201 Computational Systems Medicine

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 23, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by graduate student Roger Chang. It covers the interface between structural bioinformatics and systems biology form the viewpoint of off-target drug effects and large scale metabolic modeling.

UCSD Phar201 Protein Ligand Interactions

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 02, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers some aspects of protein ligand interactions with emphasis on SMAP for determining similar ligand binding sites and the pharmacological implications.

UCSD Phar201 Structural Domains in Proteins

submitted by: Phil

This is a podcast and slides of a lecture given on Nov 16, 2011 in the course Phar201 (http://www.sdsc.edu/pb/edu/pharm201/) at the University of California San Diego by Prof. Phil Bourne. It covers determining domains from 3D protein structure.

UCSD Phar201 Structural Aspects of Protein Protein Interactions

submitted by: Phil
This is a podcast and slides of a lecture given on Nov 4, 2011 in the course Phar201 ( http://www.sdsc.edu/pb/edu/pharm201/ ) at the University of California San Diego by Phil Bourne. It covers one methodology for determining the site of protein-protein interaction when one only has a single structural component of the complex. It is based on the paper found here http://www.sdsc.edu/pb/papers/chung05.pdf

SDSC 25th Anniversary

submitted by: Phil

This presentation describes my interactions with the San Diego Supercomputer Center (SDSC) over the past 15 years as part of the celebration of 25 years of SDSC which will take place on October 12, 2010.

Structural Bioinformatics Pharm 201 UCSD Lecture 18

submitted by: Phil

This is lecture 18 (the final lecture) from a graduate student class in structural bioinformatics offered at UCSD see http://www.sdsc.edu/pb/edu/pharm201/ The lecture covers the a brief discussion of some outstanding problems.

Structural Bioinformatics Pharm 201 UCSD Lecture 17

submitted by: Phil

This is lecture 17 from a graduate student class in structural bioinformatics offered at UCSD see http://www.sdsc.edu/pb/edu/pharm201/ The lecture covers the features of protein-protein interactions and one method to predict such interactions.

Structural Bioinformatics Pharm 201 UCSD Lecture 16

submitted by: Phil
This is lecture 16 from a graduate student class in structural bioinformatics offered at UCSD see http://www.sdsc.edu/pb/edu/pharm201/ The lecture covers molecular graphics and following a brief introduction is a class discussion of the good and bad features of various molecular graphics programs based on an assignment the class had undertaken. Namely: Render a PDB structure of protein kinase A in two or more of the following tools: jmol, Pymol, Chimera (UCSF), ICM Browser (MolSoft) and...

Structural Bioinformatics Pharm 201 UCSD Lecture 15

submitted by: Phil

This is lecture 15 from a graduate student class in structural bioinformatics offered at UCSD see http://www.sdsc.edu/pb/edu/pharm201/ The lecture covers a method for studying protein-ligand interactions. Specifically finding off-target binding sites that has implications for studying the side effects and repositioning existing drugs.