Breast and Ovarian Cancers Moon Shot update

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/podcast/breast-ovarian-cancers-moon/id431848... The moon shot for breast and ovarian cancer focuses on two diseases: triple-negative breast cancer and high-grade serous ovarian cancer. Jennifer Litton, M.D., associate professor of Breast Medical Oncology, and Shannon Westin, M.D., assistant professor of Gynecologic and Reproductive Medicine, discuss several new and exciting projects underway that can quickly make a difference in the...

Cancer screening – what you should know

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/podcast/cancer-screening-what-you/id43184821... The standard screenings for cancer are for breast, cervical, prostate and colon. For those in a high-risk category, lung, ovarian and liver cancer screenings may be recommended. Therese Bevers, M.D., medical director of Cancer Prevention at MD Anderson Cancer Center, discusses MD Anderson’s cancer screening recommendations and explains the conflicting cancer screening reports.

Cancer early detection – genetic testing

submitted by: mdanderson
Download from iTunes: https://itunes.apple.com/us/podcast/cancer-early-detection-genetic/id431... Breast cancer, ovarian cancer and colon cancer are the most common cancer types that are tested for inherited mutations. Banu Arun, M.D., professor of Breast Medical Oncology; Karen Lu, M.D., professor and chair of Gynecologic Oncology and Reproductive Medicine; and Nancy You, M.D., assistant professor of Surgical Oncology; all part of MD Anderson Cancer Center’s Clinical Cancer Genetics...

Identification and Management of Women With BRCA Mutations or Hereditary Predisposition for Breast and Ovarian Cancer

submitted by: mcgheekkm

Dr. Sandhya Pruthi, consultant in the breast diagnostic clinic at Mayo Clinic in Rochester, MN, discusses her December 2010 Mayo Clinic Proceedings article http://tinyurl.com/3x2dr7v on diagnostic and management approaches to patients with BRCA mutations that put them at higher risk of breast and/or ovarian cancer.

Fighting for Family

submitted by: heisman

Fighting for Family was produced with the aim of creating awareness in the many aspects of hereditary breast and ovarian cancer. The viewer is introduced to concepts of mendelian inheritance and gene mutation. As told through the eyes of hereditary breast and ovarian cancer gene mutation carriers, the viewers are encouraged to probe their family histories to make important decisions for themselves and future generations.

How Drosha and Dicer work in RNA interference

submitted by: mdanderson

Animated demonstration on how Dicer and Drosha work in RNA interference.

RNA Interference Proteins Tied to Cancer Survival Rates

submitted by: mdanderson
Levels of two proteins in a woman's ovarian cancer are strongly associated with her likelihood of survival, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Dec. 18 issue of the New England Journal of Medicine. The study shows that women with high levels of Dicer and Drosha, two proteins that are vital to a cell's gene-silencing machinery, had a median survival of 11 years. For those with low levels of both proteins, median survival...

The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers

submitted by: BernardFriedenson
Background The present study was designed to test the hypothesis that inactivation of virtually any component within the pathway containing the BRCA1 and BRCA2 proteins would increase the risks for lymphomas and leukemias. In people who do not have BRCA1 or BRCA2 gene mutations, the encoded proteins prevent breast/ovarian cancer. However BRCA1 and BRCA2 proteins have multiple functions including participating in a pathway that mediates repair of DNA double strand breaks by error-free...
Authors: Bernard Friedenson