Novel cell-based and materials science approach to target Glioblastoma brain cancer tumors

submitted by: nsf

Stefan Bossmann and Deryl Troyer at Kansas State University are developing a novel materials treatment method for persons with brain cancer that uses a type of white blood cell to deliver anticancer drugs to particularly virulent brain tumors.

Young breast cancer patients with early-stage disease may undergo unnecessary testing when diagnosed

submitted by: mdanderson
Download from iTunes: . More than one third of younger, early stage breast cancer patients undergo unnecessary imaging procedures – including position emission tomography (PET), computed tomography (CT), nuclear medicine bone scans (NMBS) and tumor markers (TM) -- at the time of staging and diagnosis. Carlos Barcenas, M.D., assistant professor, Breast Medical Oncology and Sharon Giordano, M.D., professor, Breast...

Breast cancer – most common cancer in women

submitted by: mdanderson
Download: Breast cancer has two main types: ductal carcinoma and lobular carcinoma. These two types of breast cancer present and behave differently but they are treated the same way. Sharon Giordano, M.D., professor in Breast Medical Oncology at The University of Texas MD Anderson Cancer Center and chair of Health Services Research, discusses the differences between ductal and lobular carcinomas including in situ...

Ovarian cancer screening with simple blood test

submitted by: mdanderson
Download from iTunes: A simple blood test currently approved to detect ovarian cancer disease recurrence is full of new possibility. It may, one day, detect invasive, high-grade disease at its earliest, most curable stage. Listen to Karen Lu, M.D., professor and chair of Gynecologic Oncology and Reproductive Medicine, as she details the findings, and what they could, one day, mean for women.

Daniel Bozinov ( at the 2012 SFAF Meeting

submitted by: JGI

Daniel Bozinov on "Challenges in Genomic Cloud Computing" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

From Tissue Slide To First Molecular Analysis within 24 hours. Fact or Fiction?

submitted by: LUMC_PA_MD
For a number of cancersubtypes it is crucial to determine if a mutation is present in genes like KRAS, EGFR, BRAF and PIK3CA. The testresults will be consequently used to predict the response to therapy. We demonstrate the workflow of this process in the Molecular Tumour Diagnostics group in the department of Pathology at the Leiden University Medical Center in the Netherlands. For more information: LUMC Pathology (Dutch only) Citation: Rapid KRAS, EGFR, BRAF and PIK3CA...

Breast Cancer -- It Doesn't Just Strike Women

submitted by: mdanderson
There were about 1,970 new cases of invasive breast cancer diagnosed among men in the United States in 2010. Yet, because of the lack of awareness, diagnosis normally happens at a late stage. Breast cancer is branded a female disease, so males must brave the pink ribbons, women-only waiting rooms, etc. There are similarities and differences in male and female breast cancer. Sharon Giordano, M.D., associate professor and internist in the Department of Breast Medical Oncology at MD...

Wnt/beta-catenin signaling is stimulated by alpha-Melanocyte-Stimulating Hormone in melanoma and melanocyte cells: implication in cell differentiation.

submitted by: bbellei
Wnt/?-catenin signaling plays important roles in many developmental processes including neural crest-derived melanocyte development and migration. However, the effective contribution of Wnt/?-catenin pathway in melanogenesis in adult human melanocytes has not been fully elucidated. Here, we report that in melanoma cells and in normal human melanocytes melanogenesis stimulation by ?-MSH induces phosphorylation of ?-catenin-Ser675 and stabilization of ?-catenin protein. Activation of PKA by...
Authors: Barbara Bellei

Fertility Preservation

submitted by: mcgheekkm

Dr. Jani Jensen, Assistant Professor in the Department of Reproduction Endocrinology and Fertility at Mayo Clinic in Rochester, MN, discusses her article on fertility preservation, (Available at: ) which appears in the January 2011 issue of Mayo Clinic Proceedings.

Dr Manish Kohli of Mayo Clinic discusses January 2010 Mayo Clinic Proceedings article on prostate cancer

submitted by: mcgheekkm

Dr. Manish Kohli of Mayo Clinic discusses his January 2010 Mayo Clinic Proceedings article ( on new developments in the medical management of prostate cancer.