Breast Cancer Coalition talk on Open Notebook Science

submitted by: jcbradley
Jean-Claude Bradley presents "Accelerating Discovery by Sharing: a case for Open Notebook Science" on May 1, 2011 at the National Breast Cancer Coalition Annual Advocacy Conference in Arlington, VA. First a few examples are provided which show how a lack of transparency in science can retard progress by creating ambiguity. Demonstrations of the use of Open Notebook Science in malaria research, solubility and other chemistry related applications then follow. Examples of web services...

Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface-Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization

submitted by: emsley
We demonstrate fast characterization of the distribution of surface bonding modes and interactions in a series of functionalized materials via surface-enhanced nuclear magnetic resonance spectroscopy using dynamic nuclear polarization (DNP). Surface-enhanced silicon-29 DNP NMR spectra were obtained by using incipient wetness impregnation of the sample with a solution containing a polarizing radical (TOTAPOL). We identify and compare the bonding topology of functional groups in materials...
Authors: Malika Boualleg, Chloé Thieuleux, Arthur Roussey, Fernando Rascon, Florent Héroguel, Pascal Miéville, Veronika Vitzthum, Marc Caporini, Anne Lesage, David Gajan, Moreno Lelli, Laurent Veyre, Geoffrey Bodenhausen, Christophe Copéret, Lyndon Emsley

NMR Fluorescense for Dynamic and Protein Folding / Aggregation Studies part 4

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Jerson L. Silva (0:00)

Competence in B. subtilis, part 2; NMR Fluorescense for Dynamic and Protein Folding / Aggregation Studies part 3

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Daniel Schultz (0:00)
Jerson L. Silva (50:20)

NMR Fluorescence for Dynamic and Protein Folding / Aggregation Studies, part 2

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Jerson L. Silva (0:00)

NMR Fluorescence for Dynamic and Protein Folding / Aggregation Studies, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Jerson L. Silva (11:30)

NMR for Protein Structural Determination and Dynamics, part 2; Magnetoglobus Multicellularis: magnetic organism, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Ana Paula Valente (0:00)
Henrique Lines de Barros (32:00)

University of the Sciences Open Chemistry Talk

submitted by: jcbradley

Jean-Claude Bradley presents on "Open Education in Chemistry Research and Classroom" at the University of the Sciences on January 11, 2011. The talk covers screencasting, wikis, chemical information validation, Open Notebook Science and smartphones.

Mirza PhD defense on the Ugi reaction for anti-malarial screening

submitted by: jcbradley
Khalid Baig Mirza defends his Ph.D. thesis at Drexel University on December 6, 2010 (advisor JC Bradley). He first discusses Open Notebook Science and his contribution to the sodium hydride oxidation controversy. Then he describes the UsefulChem project, involving the use of the Ugi reaction as an approach to synthesizing new anti-malarial agents, including a few unexpected side reactions and challenges. Finally he presents an overview of the ONS Solubility Challenge and its application to...

OpenSciNY Open Notebook Science Talk

submitted by: jcbradley
On May 14, 2010 Jean-Claude Bradley presented on Open Notebook Science at the OpenSciNY conference at the New York University Library. He introduced the topic by telling a few stories about how new forms of communication are affecting how we think about concepts like "scientific precedent", "peer review", "scientific publishing" and "scientific scholarship". At the end he spoke about archiving Open Notebook Science projects culminating in the publication of the Reaction Attempts and ONS...