This video is a surreal presentation of a Metabolic Melody by Kevin Ahern (www.davincipress.com/metabmelodies.html for more info). The tune is The Beatle's "Across the Universe." The lyrics and video are by Kevin Ahern and the recording is by David Simmons

Gouri Ghosh discusses SR Proteins' functions, how they work, and what they affect. Splicing and RNA are also involved.

Several mRNAs are specifically transported to the anterior and posterior regions of Drosophila oocytes by microtubule-based motor proteins, but the organization of microtubules in these cells is unclear. Parton et al. reveal that oocyte microtubules are highly dynamic and display a PAR-1-dependent bias in polarity that facilitates transport of oskar mRNA to the oocyte posterior. This biosights episode presents the paper by Parton et al. from the July 11, 2011, issue of The Journal of Cell...

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Tackjip Ha (0:00)
Clements (25:30)

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Tackjip Ha

During an immune response, T cells move into tissues from the vasculature by crossing the endothelial cell layer lining blood vessel walls. Heasman et al. reveal that this transendothelial migration requires signaling at both the front and back of leukocytes by the small GTPase RhoA. This biosights episode presents the paper by Heasman et al. from the August 23, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Anne Ridley. Produced by Caitlin Sedwick...

Microtubules align along the apical-basal axis of epithelial cells with their plus ends pointing to the basal side. Hotta et al. reveal how signals from the extracellular matrix establish this arrangement by recruiting the microtubule-anchoring factors LL5s to the basal cell cortex. This biosights episode presents the paper by Hotta et al. from the May 31, 2010 issue of The Journal of Cell Biology, and includes an interview with senior author Yuko Mimori-Kiyosue. Produced by Caitlin...

Alex Bateman's 2010 Benjamin Franklin Award lecture on why classification is important in science and how his team are using Wikipedia to engage the public and scientists in providing free and accurate information about RNA.

From the flu to HIV, RNA viruses challenge our immune systems like no other infectious agent on the planet. RNA viruses provide unique insights into the patterns and processes of evolutionary change in real time. The study of viral evolution is especially topical given the growing awareness that emerging and re-emerging diseases (most of which are caused by RNA viruses) represent a major threat to public health. How do RNA viruses adapt and change, and how do our bodies respond? Why are...

Biological organization is discussed within a holistic framework . A new orientation is presented of natural processes with an approach in model construction that is focused strictly on physical form and centered away from abstractions that escape the perceptual senses, lead towards the postulation of non-verifiable and non-witnessible entities. A universal construction composed of first perspective representations of path, witness as unique loci in volumes of space delineated as...