organic chemistry

Jean-Claude Bradley presents the first lecture of Organic Chemistry I (CHEM241) of the Winter 2012 term at Drexel University. This introduces the course and provides details of how the course will proceed.

Jean-Claude Bradley presents a 15 minute summary of current research in his lab on September 29, 2011 at the Drexel University Department of Chemistry Faculty Mini-Symposium. The main project discussed is the Open Melting Point Collection done in collaboration with Andrew Lang and Antony Williams. Work by Evan Curtin is also shown, demonstrating the application of melting point and solubility in reaction design.

Jean-Claude Bradley presents the second lecture for Chemical Information Retrieval at Drexel University for Fall 2011 on September 30, 2011. The talk covers finding chemical property data on free and commercial databases, including Reaxys, SciFinder, ChemSpider and Google. An example is shown where an incorrect melting point for diazepam on the web and Reaxys was identified by carefully reading the original article. The use of Google Apps Scripts and other web services are covered. Finally...

Jean-Claude Bradley presents the introductory lecture for Chemical Information Retrieval at Drexel University for Fall 2011 on September 23, 2011. Examples are given to demonstrate how difficult it can be to find and assess chemical information such as melting points. An overview of the class wiki is then given.

Jean-Claude Bradley presented at a panel on New Forms of Scholarly Communication in Science at the Special Libraries Association meeting on June 15, 2011. The talk covered the role of trust in science, with a focus on the validation of melting point data. Where the literature was unable to reconcile measurements, Open Notebook Science was used to clarify. The collection of an Open Dataset of melting point measurements for 20,000 compounds was described as well as ongoing curation efforts...

Jean-Claude Bradley presents on "Open Education in Chemistry Research and Classroom" at the University of the Sciences on January 11, 2011. The talk covers screencasting, wikis, chemical information validation, Open Notebook Science and smartphones.

This is the Jan 3, 2011 introductory lecture for Organic Chemistry II (CHEM242-002) by Jean-Claude Bradley at Drexel University.

Khalid Baig Mirza defends his Ph.D. thesis at Drexel University on December 6, 2010 (advisor JC Bradley). He first discusses Open Notebook Science and his contribution to the sodium hydride oxidation controversy. Then he describes the UsefulChem project, involving the use of the Ugi reaction as an approach to synthesizing new anti-malarial agents, including a few unexpected side reactions and challenges. Finally he presents an overview of the ONS Solubility Challenge and its application to...

Jean-Claude Bradley presents a condensed version of ongoing work in his laboratory at Drexel University. Topics covered include Open Notebook Science for malaria drug discovery, the Ugi reaction and the ONS Challenge, a crowdsourcing initiative to collect non-aqueous solubility measurements. Some recent work on using web services to leverage these datasets is also discussed.

On May 14, 2010 Jean-Claude Bradley presented on Open Notebook Science at the OpenSciNY conference at the New York University Library. He introduced the topic by telling a few stories about how new forms of communication are affecting how we think about concepts like "scientific precedent", "peer review", "scientific publishing" and "scientific scholarship". At the end he spoke about archiving Open Notebook Science projects culminating in the publication of the Reaction Attempts and ONS...