Rolling circle amplification is used to create nanoparticles which consist of long single stranded DNA of an immunogenic sequence, specifically, a...
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Rolling circle amplification is used to create nanoparticles which consist of long single stranded DNA of an immunogenic sequence, specifically, a CpG sequence. The ssDNA coils into a spherical nanoparticle structure which will stimulate the patients own immune system to rid itself of cancer.