User Profile


Jennifer Smith
Specialized Professional
Milwaukee, WI
Research Interests:
Bioinformatics, Databases, Gene Curation, Ontologies, Molecular Biology
About jennifer.r.smith:
I am a Scientific Curator at the Rat Genome Database. RGD is housed at the Medical College of Wisconsin.
Publications in PubMed
  1. Dwinell MR, Worthey EA, Shimoyama M, Bakir-Gungor B, DePons J, Laulederkind S, Lowry T, Nigram R, Petri V, Smith J, Stoddard A, Twigger SN, Jacob HJ, . The Rat Genome Database 2009: variation, ontologies and pathways. Nucleic acids research 2009 37. DOI:10.1093/nar/gkn842.
  2. Twigger SN, S Smith J, Zuniga-Meyer A, Bromberg SK. Exploring phenotypic data at the rat genome database. Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.] 2006 Chapter 1. DOI:10.1002/0471250953.bi0114s14.
  3. Twigger SN, Pasko D, Nie J, Shimoyama M, Bromberg S, Campbell D, Chen J, dela Cruz N, Fan C, Foote C, Harris G, Hickmann B, Ji Y, Jin W, Li D, Mathis J, Nenasheva N, Nigam R, Petri V, Reilly D, Ruotti V, Schauberger E, Seiler K, Slyper R, Smith J, Wang W, Wu W, Zhao L, Zuniga-Meyer A, Tonellato PJ, Kwitek AE, Jacob HJ. Tools and strategies for physiological genomics: the Rat Genome Database. Physiological genomics 2005 23(2). DOI:10.1152/physiolgenomics.00040.2005.
  4. Twigger SN, Shimoyama M, Bromberg S, Kwitek AE, Jacob HJ, . The Rat Genome Database, update 2007--easing the path from disease to data and back again. Nucleic acids research 2007 35. DOI:10.1093/nar/gkl988.
  5. Davids BJ, Palm JE, Housley MP, Smith JR, Andersen YS, Martin MG, Hendrickson BA, Johansen FE, Svärd SG, Gillin FD, Eckmann L. Polymeric immunoglobulin receptor in intestinal immune defense against the lumen-dwelling protozoan parasite Giardia. Journal of immunology (Baltimore, Md. : 1950) 2006 177(9). DOI:10.1093/nar/gkl988.
  6. Maaser C, Housley MP, Iimura M, Smith JR, Vallance BA, Finlay BB, Schreiber JR, Varki NM, Kagnoff MF, Eckmann L. Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infection and immunity 2004 72(6). DOI:10.1128/IAI.72.6.3315-3324.2004.
  7. Eckmann L, Smith JR, Housley MP, Dwinell MB, Kagnoff MF. Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella. The Journal of biological chemistry 2000 275(19). DOI:10.1128/IAI.72.6.3315-3324.2004.
  8. Eckmann L, Stenson WF, Savidge TC, Lowe DC, Barrett KE, Fierer J, Smith JR, Kagnoff MF. Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. The Journal of clinical investigation 1997 100(2). DOI:10.1172/JCI119535.
  9. Eckmann L, Reed SL, Smith JR, Kagnoff MF. Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha. The Journal of clinical investigation 1995 96(3). DOI:10.1172/JCI118161.
  10. Eckmann L, Huang GT, Smith JR, Morzycka-Wroblewska E, Kagnoff MF. Increased transcription and coordinate stabilization of mRNAs for secreted immunoglobulin alpha heavy chain and kappa light chain following stimulation of immunoglobulin A expressing B cells. The Journal of biological chemistry 1994 269(52). DOI:10.1172/JCI118161.
  11. Eckmann L, Morzycka-Wroblewska E, Smith JR, Kagnoff MF. Cytokine-induced differentiation of IgA B cells: studies using an IgA expressing B-cell lymphoma. Immunology 1992 76(2). DOI:10.1172/JCI118161.