JCB's videos (77)


518
Jan 23, 2012
Septins rein in the membrane

T cells require the septin family of GTP-binding proteins to maintain the integrity of their plasma membranes as they...

447
Jan 9, 2012
A Twin-Track Approach to Building Desmosomes

Desmosomes are intercellular adhesions whose adhesive core is formed by two distinct classes of cadherin molecules --...

434
Nov 29, 2011
CKIδ Decentralizes the Centrosome

When a T cell encounters a target antigen-presenting cell, the lymphocyte's centrosome relocalizes to a specialized...

442
Oct 31, 2011
Cofilin severs the ties between cytokinetic nodes

Cytokinetic nodes are precursor structures that assemble into the actomyosin contractile ring that separates daughter...

573
Oct 3, 2011
Moesin keeps mitotic cells in shape

The ERM protein Moesin helps mitotic cells undergo a series of dramatic shape changes by linking the actin...

665
Sep 9, 2011
Actin puts the squeeze on Weibel-Palade bodies

The actin cytoskeleton has been proposed to regulate exocytosis in many different ways. Nightingale et al. use a...

1037
Aug 10, 2011
Nuclear envelope starts with a clean sheet

At the start of mitosis, the nuclear envelope and nuclear pore complexes break down and disperse into the endoplasmic...

1016
Jul 11, 2011
Oocyte microtubules show their bias

Several mRNAs are specifically transported to the anterior and posterior regions of Drosophila oocytes by...

1085
Jun 13, 2011
Tying the Golgi Ribbon to the Centrosome

The mammalian Golgi apparatus exists as a continuous ribbon that clusters around the centrosome, but the significance...

968
May 16, 2011
Ouch! Single Cell Wound Repair in Drosophila Embryos

Individual cells must quickly repair any disruptions to their plasma membrane. Abreu-Blanco et al. describe how early...

1074
Apr 20, 2011
How the ER shapes up and ships out

The endoplasmic reticulum is a complex network of interconnected membrane tubules and cisternae. West et al. use...

1159
Mar 22, 2011
Nup133 is a Pore Relation to the Centrosome

The centrosome remains closely associated with the nucleus throughout the cell cycle. Bolhy et al. reveal that the...

1011
Feb 23, 2011
Curbing the Killer Instinct

Natural Killer (NK) cells distinguish target cells from surrounding healthy tissue by integrating signals from a...

1192
Jan 24, 2011
Microtubules Keep Tumor Cells Breathing Easy

The transcription factor HIF-1α is essential for a cell's response to low oxygen conditions. Carbonaro et al....