JCB's videos (74)


522
Jan 4, 2013
biosights: Decemeber 24, 2012 - Global sourcing for cytokinetic ring assembly

At the end of cytokinesis, the microtubule-rich midbody connecting the daughter cells is either shed into the...

439
Nov 27, 2012
biosights: November 26, 2012 - Global sourcing for cytokinetic ring assembly

Fission yeast are thought to assemble their cytokinetic actomyosin rings from actin filaments nucleated at...

593
Nov 12, 2012
biosights: October 29, 2012 - A stiff test for collectively migrating cells

The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but...

566
Oct 1, 2012
biosights: October 1, 2012 - Cortical dynein puts the spindle in its place

The position of the mitotic spindle is controlled by the microtubule-based motor dynein and a ternary complex of the...

566
Aug 8, 2012
biosights: August 6, 2012 - Redistribution aids the pore

In animal cells, the nuclear lamina keeps nuclear pore complexes evenly distributed throughout the nuclear envelope....

527
Jul 9, 2012
Asters help embryonic nuclei find their own space

In early Drosophila embryos, nuclei undergo rapid, synchronous divisions without being separated into individual...

537
Jun 12, 2012
T cell signaling goes with the flow

Activated T cell receptors stimulate actin polymerization at the periphery of the immunological synapses that form...

583
May 14, 2012
A new way forward for fibroblasts

Fibroblasts moving across two-dimensional surfaces form lamellipodial protrusions at their leading edge, but how...

506
May 1, 2012
PI3K's Pivotal Role in Cell Migration

Phosphoinositide 3-kinase (PI3K) and its phospholipid products are polarized toward the front of migrating...

384
Mar 20, 2012
Vinculin minds the endothelial gap

The adhesions between endothelial cells transiently remodel in response to angiogenic growth factors and inflammatory...

380
Feb 21, 2012
Neuronal autophagosomes mature on the move

Autophagy is a cellular degradation pathway essential for neuronal survival, but little is known about the dynamics...

505
Jan 23, 2012
Septins rein in the membrane

T cells require the septin family of GTP-binding proteins to maintain the integrity of their plasma membranes as they...

430
Jan 9, 2012
A Twin-Track Approach to Building Desmosomes

Desmosomes are intercellular adhesions whose adhesive core is formed by two distinct classes of cadherin molecules --...

415
Nov 29, 2011
CKIδ Decentralizes the Centrosome

When a T cell encounters a target antigen-presenting cell, the lymphocyte's centrosome relocalizes to a specialized...