JCB's videos (68)


514
Feb 18, 2014
biosights: February 17, 2014 - Shroom takes embryos to new dimensions

During development, the planar polarized distribution of Rho kinase and Myosin II helps Drosophila germ-band cells...

506
Oct 3, 2011
Moesin keeps mitotic cells in shape

The ERM protein Moesin helps mitotic cells undergo a series of dramatic shape changes by linking the actin...

492
Jul 9, 2012
Asters help embryonic nuclei find their own space

In early Drosophila embryos, nuclei undergo rapid, synchronous divisions without being separated into individual...

490
Jan 4, 2013
biosights: Decemeber 24, 2012 - Global sourcing for cytokinetic ring assembly

At the end of cytokinesis, the microtubule-rich midbody connecting the daughter cells is either shed into the...

489
Jan 28, 2013
biosights: January 21, 2013 - How cell shape changes unfold

Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al....

483
Dec 23, 2013
biosights: Decemeber 23, 2013 - Tumor cells WASH away the extracellular matrix

Tumor cells invade through extracellular matrices by forming actin-rich structures called invadopodia, which contain...

480
Sep 30, 2013
biosights: September 30, 2013 - The nodal network

In addition to specialized actin structures such as lamellipodia and stress fibers, cells are thought to contain a...

477
Feb 21, 2013
biosights: February 18, 2013 - Erecting a myosin scaffold for cytokinesis

Cell division requires the coordinated action of proteins that promote actomyosin contraction, membrane trafficking,...

469
Jan 23, 2012
Septins rein in the membrane

T cells require the septin family of GTP-binding proteins to maintain the integrity of their plasma membranes as they...

462
May 1, 2012
PI3K's Pivotal Role in Cell Migration

Phosphoinositide 3-kinase (PI3K) and its phospholipid products are polarized toward the front of migrating...

460
Apr 17, 2013
biosights: April 15, 2013 - Frog oocytes evade the checkpoint

Most dividing cells possess a spindle assembly checkpoint that prevents them from entering anaphase until all their...

455
Oct 28, 2013
biosights: October 28, 2013 - A framework for understanding muscle microtubules

The microtubules of skeletal muscle fibers are arranged into an orthogonal grid, but how this network is formed is...

424
Jul 16, 2013
biosights: July 8, 2013 - Vinculin delivers a clutch performance

At the leading edge of migrating cells, actin assembly and membrane protrusion are closely coupled with the formation...

417
Aug 6, 2013
biosights: August 5, 2013 - Epithelia restored by healing waves

Epithelial cells around the edge of a wound assemble an actomyosin cable that constricts to draw the wound closed,...