Individual cells must quickly repair any disruptions to their plasma membrane. Abreu-Blanco et al. describe how early...

The actin cytoskeleton has been proposed to regulate exocytosis in many different ways. Nightingale et al. use a...

During the first meiotic division of mammalian oocytes, the meiotic spindle and chromosomes move from the interior to...

The ERM protein Moesin helps mitotic cells undergo a series of dramatic shape changes by linking the actin...

In early Drosophila embryos, nuclei undergo rapid, synchronous divisions without being separated into individual...

When leukocytes enter or exit the blood stream, they leave small wounds both in and between the vascular endothelial...

In animal cells, the nuclear lamina keeps nuclear pore complexes evenly distributed throughout the nuclear envelope....

Fibroblasts moving across two-dimensional surfaces form lamellipodial protrusions at their leading edge, but how...

The position of the mitotic spindle is controlled by the microtubule-based motor dynein and a ternary complex of the...

At the end of cytokinesis, the microtubule-rich midbody connecting the daughter cells is either shed into the...

Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al....

T cells require the septin family of GTP-binding proteins to maintain the integrity of their plasma membranes as they...

The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but...

Phosphoinositide 3-kinase (PI3K) and its phospholipid products are polarized toward the front of migrating...