JCB's videos (69)


1552
Mar 22, 2010
Integrating the forces that fold tissues

During gastrulation, pulsed contractions of the actomyosin cytoskeleton apically constrict a strip of cells on the...

1537
May 27, 2010
A Turning Point for Macrophages

Drosophila macrophages disperse themselves around the body during embryogenesis, ready to mount an immune response at...

1335
Oct 5, 2010
Dynein and kinesin generate nuclear power

Many cellular processes, including polarization and differentiation, require the nucleus to move to a specific...

1229
Nov 2, 2010
Pulling centrosomes to the forward position

Most migrating cells place their centrosome in front of the nucleus, facing the direction in which the cell is...

1205
Aug 11, 2010
Acetylated microtubules let the ER slide

The endoplasmic reticulum is highly dynamic, although little is known about why and how its membrane tubules move....

1197
Sep 14, 2010
T Cells Rho across the endothelium

During an immune response, T cells move into tissues from the vasculature by crossing the endothelial cell layer...

1156
Jan 24, 2011
Microtubules Keep Tumor Cells Breathing Easy

The transcription factor HIF-1α is essential for a cell's response to low oxygen conditions. Carbonaro et al....

1117
Mar 22, 2011
Nup133 is a Pore Relation to the Centrosome

The centrosome remains closely associated with the nucleus throughout the cell cycle. Bolhy et al. reveal that the...

1089
Sep 3, 2014
biosights: September 1, 2014 - Deploying exosomes in a battle of the sexes

The paired accessory glands of male Drosophila secrete multiple signaling factors into the seminal fluid that promote...

1020
Apr 20, 2011
How the ER shapes up and ships out

The endoplasmic reticulum is a complex network of interconnected membrane tubules and cisternae. West et al. use...

1019
Jun 13, 2011
Tying the Golgi Ribbon to the Centrosome

The mammalian Golgi apparatus exists as a continuous ribbon that clusters around the centrosome, but the significance...

1003
Nov 25, 2013
biosights: November 25, 2013 - Caspases work as branch managers

When a growing axon nears its target, it arborizes, or branches, to form numerous synaptic connections. Campbell and...

998
Nov 29, 2010
Seeing organelles live in concert

Centrosome positioning is thought to be important for both neuronal migration and axonogenesis. To investigate...

986
Aug 10, 2011
Nuclear envelope starts with a clean sheet

At the start of mitosis, the nuclear envelope and nuclear pore complexes break down and disperse into the endoplasmic...