JCB's videos (71)


6743
Apr 22, 2009
Collective cell migration requires vesicular trafficking for chemoattractant...

Chemoattractant signaling induces the polarization and directed movement of cells secondary to the activation of...

3701
Apr 22, 2009
Cdc42 controls spindle orientation to position the apical surface during...

The establishment of apical–basal polarity within a single cell and throughout a growing tissue is a key feature of...

3599
Apr 22, 2009
One-Dimensional Topography Underlies Three-Dimensional Fibrillar Cell Migration

Current concepts of cell migration were established in regular two-dimensional (2D) cell culture, but the roles of...

3515
Aug 11, 2009
Multiparametric analysis of focal adhesion formation by RNAi-mediated gene...

Cell adhesion to the extracellular matrix is mediated by elaborate networks of multiprotein complexes consisting of...

2994
Oct 22, 2009
DNA replication times the cell cycle and contributes to the mid-blastula...

We examined the contribution of S phase in timing cell cycle progression during Drosophila embryogenesis using an...

2770
Jul 14, 2009
Motor-dependent microtubule disassembly driven by tubulin tyrosination

In cells, stable microtubules (MTs) are covalently modified by a carboxypeptidase, which removes the C-terminal Tyr...

2222
Nov 2, 2009
AP-1 and KIF13A coordinate endosomal sorting and positioning during...

Specialized cell types exploit endosomal trafficking to deliver protein cargoes to cell type–specific...

2193
Oct 22, 2009
The Dictyostelium type V myosin MyoJ is responsible for the cortical...

The contractile vacuole (CV) complex in Dictyostelium is a tubulovesicular osmoregulatory organelle that exhibits...

1897
Jul 16, 2010
Long Asters Rock The Spindle

Astral microtubules help position the cytokinetic furrow by confining actomyosin contractility to the cell equator....

1840
Jun 15, 2010
Laminin Adhesions Help Microtubules Reach Base

Microtubules align along the apical-basal axis of epithelial cells with their plus ends pointing to the basal side....

1810
Jan 28, 2010
Systems biology of the mitotic spindle

A novel high-throughput screening approach that combines yeast mutant arrays with high-content imaging provides fresh...

1779
Apr 20, 2010
CyclinB1-Cdk1 Makes Its Move

Cells drastically alter their structure at the onset of mitosis. Gavet and Pines reveal that the mitotic kinase...

1715
May 12, 2014
biosights: May 12, 2014 - Phosphoinositides get cells in shape

Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an...

1709
Feb 24, 2010
Probing the spindle matrix

A microtubule-independent network of proteins called the spindle matrix is involved in assembling mitotic and meiotic...