JCB's videos (74)


172
Feb 19, 2015
biosights: February 16, 2015 - Filopodia point the way for haptotaxis

Migrating fibroblasts maintain or change their direction by branching off new lamellipodia from existing protrusions...

473
Jan 20, 2015
biosights: January 19, 2015 - Tubulin transport pumps up cilia

The assembly of cilia and flagella requires the delivery of large amounts of tubulin to the growing ends of the...

667
Jan 5, 2015
biosights: December 22, 2014 - Osmotic gradient is just the tonic for wounded...

Rapid wound repair is generally thought to be initiated by intrinsic cues, such as changes in the structure or...

226
Nov 25, 2014
biosights: November 24, 2014 - Dynein helps centrioles stick together

Dynein has numerous functions in mitosis, but the function of the motor complex's light intermediate chains is poorly...

717
Oct 27, 2014
biosights: October 27, 2014 - Epithelial cells make changes at the top

The apical surfaces of polarized epithelia are covered by short, actin-rich protrusions called microvilli, but what...

360
Sep 30, 2014
biosights: September 29, 2014 - Cdc42 prompts a change of heart

The Drosophila heart is a simple tubular structure with a central lumen. Vogler et al. reveal that the small GTPase...

1246
Sep 3, 2014
biosights: September 1, 2014 - Deploying exosomes in a battle of the sexes

The paired accessory glands of male Drosophila secrete multiple signaling factors into the seminal fluid that promote...

542
Aug 4, 2014
biosights: August 4, 2014 - Rok keeps its finger on the pulse of apical...

Early in Drosophila embryogenesis, contractile pulses of myosin assembly and disassembly constrict the apical domains...

340
Jul 8, 2014
biosights: July 7, 2014 - The fluid dynamics of collective cell migration

During development and tumor metastasis, cells prepare to migrate by undergoing an epithelial-to-mesenchymal...

447
Jun 12, 2014
biosights: June 9, 2014 - Rab18 tilts the balance of ER structure

The endoplasmic reticulum consists of peripheral tubular networks connected to sheet-like domains surrounding the...

1737
May 12, 2014
biosights: May 12, 2014 - Phosphoinositides get cells in shape

Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an...

505
Apr 14, 2014
biosights: April 14, 2014 - An actin lever flattens out the cell

The lamella is a broad, flat region that forms at the front of migrating cells and adheres to the underlying...

895
Mar 24, 2014
biosights: March 17, 2014 - Blebs lead the way in Dictyostelium chemotaxis

Membrane blebs can help the leading edge of migrating cells protrude forwards, but the contribution of blebs to the...

573
Feb 18, 2014
biosights: February 17, 2014 - Shroom takes embryos to new dimensions

During development, the planar polarized distribution of Rho kinase and Myosin II helps Drosophila germ-band cells...