JCB's videos (67)


278
Aug 4, 2014
biosights: August 4, 2014 - Rok keeps its finger on the pulse of apical...

Early in Drosophila embryogenesis, contractile pulses of myosin assembly and disassembly constrict the apical domains...

87
Jul 8, 2014
biosights: July 7, 2014 - The fluid dynamics of collective cell migration

During development and tumor metastasis, cells prepare to migrate by undergoing an epithelial-to-mesenchymal...

256
Jun 12, 2014
biosights: June 9, 2014 - Rab18 tilts the balance of ER structure

The endoplasmic reticulum consists of peripheral tubular networks connected to sheet-like domains surrounding the...

1551
May 12, 2014
biosights: May 12, 2014 - Phosphoinositides get cells in shape

Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an...

356
Apr 14, 2014
biosights: April 14, 2014 - An actin lever flattens out the cell

The lamella is a broad, flat region that forms at the front of migrating cells and adheres to the underlying...

766
Mar 24, 2014
biosights: March 17, 2014 - Blebs lead the way in Dictyostelium chemotaxis

Membrane blebs can help the leading edge of migrating cells protrude forwards, but the contribution of blebs to the...

486
Feb 18, 2014
biosights: February 17, 2014 - Shroom takes embryos to new dimensions

During development, the planar polarized distribution of Rho kinase and Myosin II helps Drosophila germ-band cells...

548
Jan 21, 2014
biosights: January 20, 2014 - Motors give a new twist to platelet activation

The discoid shape of resting platelets is maintained by a peripheral ring of bundled microtubules called the marginal...

474
Dec 23, 2013
biosights: Decemeber 23, 2013 - Tumor cells WASH away the extracellular matrix

Tumor cells invade through extracellular matrices by forming actin-rich structures called invadopodia, which contain...

901
Nov 25, 2013
biosights: November 25, 2013 - Caspases work as branch managers

When a growing axon nears its target, it arborizes, or branches, to form numerous synaptic connections. Campbell and...

441
Oct 28, 2013
biosights: October 28, 2013 - A framework for understanding muscle microtubules

The microtubules of skeletal muscle fibers are arranged into an orthogonal grid, but how this network is formed is...

473
Sep 30, 2013
biosights: September 30, 2013 - The nodal network

In addition to specialized actin structures such as lamellipodia and stress fibers, cells are thought to contain a...

736
Sep 3, 2013
biosights: September 2, 2013 - Shrinking microtubules pull the centrosome...

When a T cell encounters a target antigen-presenting cell, it moves its centrosome to the immunological synapse that...

398
Aug 6, 2013
biosights: August 5, 2013 - Epithelia restored by healing waves

Epithelial cells around the edge of a wound assemble an actomyosin cable that constricts to draw the wound closed,...