apryl's Videos

Small Regulatory RNAs May Sharpen Spatial Expression Patterns
The precise establishment of gene expression patterns is a crucial step in development. Formation of a sharp boundary between high and low spatial expression domains requires a genetic mechanism...

Bacterial Inclusion Bodies Contain Amyloid-Like Structure
Protein aggregation is a process in which identical proteins self-associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as amorphous, lacking any...

Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency....

Earthquake Simulations
Kim Bak Olsen, Associate Professor Department of Geological Sciences at San Diego State University, California discusses earthquake simulations and implication this could have for structure...

StarCAVE: A Virtual Environment
Dr. Jürgen P. Schulze discusses "StarCAVE: A Virtual Environment."

Antibody-protein interactions: benchmark datasets and prediction tools evaluation
Background The ability to predict antibody binding sites (aka antigenic determinants or B-cell epitopes) for a given protein is a precursor to new vaccine design and...

Drug Discovery: African Sleeping Sickness
Rommie Amaro, Computational and Theoretical Biophysical Chemist, discusses how she uses the resources at SDSC to conduct her drug discovery research on African Sleeping Sickness. Originally posted...

Transforming Science and Society Through Cyberinfrastructure
Located on the northwest end of the University of California, San Diego is the San Diego Supercomputer Center. Home to what National Science Director Arden L Bement calls “the engine for change...

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.
In the spinal cord, motor neurons (MNs) with similar muscle targets and sensory inputs are grouped together into motor pools. To date, relatively little is known about the molecular mechanisms that...

Visualizing the ground motions of the 1906 San Francisco earthquake
With advances in computational capabilities and refinement of seismic wave-propagation models in the past decade large three-dimensional simulations of earthquake ground motion have become...