Intracellular Parasitism by Trypanosoma cruzi and Leishmania": Part 3: Current Research: Strategies for Cell Invasion and Intracellular Survival (33:43)"

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In the third part of this lecture, I will discuss current work from our laboratory on mechanisms used by the intracellular parasites Trypanosoma cruzi and Leishmania to interact with mammalian cells. In addition to clarifying specific molecular strategies used by these parasites to infect and survive within host cells, these studies also led, in some instances, to unexpected insights on novel pathways regulating mammalian cell function.

Intracellular Parasitism by Trypanosoma cruzi and Leishmania: Part 2: Leishmania spp and Leishmaniasis (13:36)

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In the second part of this lecture, I will present background material on Leishmania, the intracellular protozoan parasites responsible for severe human pathology in several parts of the world. I will discuss the main disease forms, the history of identification of the causative agent and form of transmission, and recent discoveries that established important concepts in our understanding of this increasingly serious infectious disease.

Sperm Selection for In Vitro Fertilization

submitted by: alex01

G. Huszar, MD - G. Huszar developed hyaluronic acid (HA) binding test for sperm selection for in vitro fertilization. The test allows better assessment of sperm maturity than previously used motility test. Dr. Huszar discusses also safety of cryopreservation of sperms and potential for male contraceptive drugs.

Intracellular Parasitism by Trypanosoma cruzi and Leishmania by Norma Andrews, April 2007 - Part 1: Trypanosoma cruzi and Chagas' Disease (19:23)

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Trypanosoma cruzi and Leishmania are closely related intracellular protozoan parasites that cause serious diseases throughout the world. In the first part of this lecture, I will present background material on the biology of Trypanosoma cruzi and the history of its discovery as an important agent of human disease in Latin America. I will also discuss the main characteristics of the disease, and the current efforts to stop human transmission. For more information see:...

Female Fertility

submitted by: alex01

E.Seli, MD pioneered the use of RAMAN spectroscopy in embryo assessment after in vitro fertilization. The procedure uses various biomarkers to improve pregnancy outcome.
Experimental production of oocytes from stem cells and possible role of leukemia inhibitory factor (LIF) in female fertility are also discussed.