Apoptosis: Part 2: Factors Involved in the Intrinsic Pathway of Apoptosis (27:39)

submitted by: scivee-team
Apoptosis a form of programmed cell death that plays important roles during animal development, immune response, elimination of damaged cells, and maintenance of tissue homeostasis. Apoptosis is executed by intracellular proteases named caspases that are activated during the onset of apoptosis by extrinsic and intrinsic pathways. The intrinsic pathway is triggered by the release of proteins such as cytochrome c from mitochondria to cytosol and the extrinsic pathway is activated by the...

Conus Peptides: Part 3: Conus Peptide Genes a "Drug Development Program" (25.36)

submitted by: scivee-team
Although snails are not the first animals that come to mind when venoms are mentioned, there are in fact a large number (~10,000 species) of different venomous predatory snails. The most intensively studied of these are the cone snails (Conus), which have a large number of peptide neurotoxins present in their venoms. Some cone snail venoms are lethal to man; one species causes a 70% fatality rate. How these venoms have been used to understand the nervous system, and how the characterization...