Surgical periodontal therapy with and without initial scaling and root planing in the management of chronic periodontitis: a randomized clinical trial

submitted by: drmanar
Aim: To compare the outcomes of surgical periodontal therapy with and without initial scaling and root planing. Methods: Twenty-four patients with severe chronic periodontitis were enrolled in this pilot, randomized controlled clinical trial. Patients were equally allocated into two treatment groups: Control group was treated with scaling and root planing, re-evaluation, followed by Modified Widman Flap surgery and test group received similar surgery without scaling and root planing....
Authors: Manar Aljateeli

Soft tissue wound healing around teeth and dental implants

submitted by: zmkbern
Abstract Aim: To provide an overview on the biology and soft tissue wound healing around teeth and dental implants. Material and Methods: This narrative review focuses on cell biology and histology of soft tissue wounds around natural teeth and dental implants. Results and conclusions: The available data indicate that: (a) Oral wounds follow a similar pattern. (b) The tissue specificities of the gingival, alveolar and palatal mucosa appear to be innately and not necessarily functionally...
Authors: A Sculean, R Gruber, DD Bosshardt

Clathrin-mediated endocytosis regulates occludin, and not focal adhesion, distribution during epithelial wound healing

submitted by: RappoportLab
BACKGROUND INFORMATION: Vesicle trafficking has long been suggested to play mechanistic roles in regulating directed cell migration. Recent evidence demonstrates that specific cell types and modes of migration involve transport of particular cargo through particular pathways. Epithelial wound healing is essential in tissue repair. However, investigations into the mechanisms regulating cell migration have mainly focused upon other models such as fibroblast-derived cells. Roles for vesicle...
Authors: Sarah Fletcher, Natalie Poulter, Elizabeth Haining, Joshua Rappoport