Health effect of the New Nordic Diet in adults with increased waist circumference: a 6-mo randomized controlled trial.

submitted by: skp
BACKGROUND: The regional Mediterranean Diet has been associated with lower risk of disease. OBJECTIVE: We tested the health effects of the New Nordic Diet (NND), which is a gastronomically driven regional, organic, and environmentally friendly diet, in a carefully controlled but free-living setting. DESIGN: A total of 181 centrally obese men and women, with a mean (range) age of 42 y (20-66 y), body mass index (in kg/m(2)) of 30.2 (22.6-47.3), and waist circumference of 100 cm (80-138...
Authors: Sanne Kellebjerg Poulsen, Anette Due, Andreas Jordy, Bente Kiens, Ken D Stark, Steen Stender, Claus Holst, Arne Astrup, Thomas Meinert Larsen

Evidence-Based Strategies in Weight Loss Mobile Apps

submitted by: spagoto
Background: Physicians have limited time for weight-loss counseling, and there is a lack of resources to which they can refer patients for assistance with weight loss. Weight-loss mobile applications (apps) have the potential to be a helpful tool, but the extent to which they include the behavioral strategies included in evidence-based interventions is unknown. Purpose: The primary aims of the study were to determine the degree to which commercial weightloss mobile apps include the...
Authors: Sherry Pagoto, Kristin Schneider, Mirjana Jojic, Michelle DeBiasse, Devin Mann

Association between water consumption and body weight outcomes: a systematic review

submitted by: Rebecca
BACKGROUND Drinking water is often applied as a dietary means for weight loss and overweight/obesity prevention, but no evidence-based recommendation exists for this indication. OBJECTIVE We summarized the existing evidence on the association between water consumption and body weight outcomes in adults of any body weight status. DESIGN In a systematic review, we retrieved studies from 4 electronic databases (MEDLINE, EMBASE, CINAHL, and COCHRANE), cross-references by PubMed functions...
Authors: R Muckelbauer, G Sarganas, A Grüneis, J Müller-Nordhorn

Weight-loss diets in people with type 2 diabetes and renal disease: a randomized controlled trial of the effect of different dietary protein amounts

submitted by: Peter Clifton
ABSTRACT Background: Higher-protein weight-loss diets (defined as >25% of energy as protein) are not recommended for individuals with type 2 diabetes because of their potential adverse effect on renal function. Objective: We aimed to examine the effect of such diets on renal function over 12 mo in people with type 2 diabetes and early renal disease. Design: Overweight and obese people with type 2 diabetes were screened to identify those with an albumin:creatinine ratio from 3 to...
Authors: David Jesudason, Eva Pedersen, Peter Clifton

Weight loss, weight maintenance, and adaptive thermogenesis

submitted by: stefancamps
Background: Diet-induced weight loss is accompanied by adaptive thermogenesis, ie, a disproportional or greater than expected reduction of resting metabolic rate (RMR). Objective: The aim of this study was to investigate whether adaptive thermogenesis is sustained during weight maintenance after weight loss. Design: Subjects were 22 men and 69 women [mean 6 SD age: 40 6 9 y; body mass index (BMI; in kg/m2): 31.9 6 3.0]. They followed a very-low-energy diet for 8 wk, followed by a...
Authors: Stefan Camps, Sanne Verhoef, Klaas Westerterp

Vitamin D supplementation and calcium absorption during caloric restriction: a randomized double blind trial

submitted by: shapses
Background: Weight loss (WL) is associated with a decrease in calcium absorption and may be one mechanism that induces bone loss with weight reduction. Objective: Because vitamin D supplementation has been shown to increase true fractional calcium absorption (TFCA), the goal of this study was to examine the effect of vitamin D during WL or weight maintenance (WM). Design: A randomized, placebo-controlled, double-blind 6-wk study was conducted in 82 postmenopausal women [BMI (in kg/...
Authors: Sue Shapses, Deeptha Sukumar, Stephen Schneider, Yvette Schlussel, Robert Sherrell, M Paul Field, Hasina Ambia-Sobhan

Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials

submitted by: tom_witches
Background: It is currently unclear whether altering the carbohydrate-to-protein ratio of low-fat, energy-restricted diets augments weight loss and cardiometabolic risk markers. Objective: The objective was to conduct a systematic review and meta-analysis of studies that compared energy-restricted, isocaloric, high-protein, low-fat (HP) diets with standard-protein, low-fat (SP) diets on weight loss, body composition, resting energy expenditure (REE), satiety and appetite, and...
Authors: Thomas Wycherley, Lisa Moran, Peter Clifton, Manny Noakes, Grant Brinkworth

Effect of alginate supplementation on weight loss in obese subjects completing a 12-wk energy-restricted diet: a randomized controlled trial

submitted by: mekr@life.ku.dk
Background: Acute studies with alginate-based preloads suggested that these strong gelling fibers may induce increased feelings of satiety and reduce energy intakes. However, the long-term efficacy and safety of alginate supplementation on body weight regulation are lacking. Objective: The primary aim of the study was to investigate the effects in subjects of alginate supplementation in conjunction with energy restriction (2300 kcal/d) on loss of body weight and fat and, second, on...
Authors: Morten Georg Jensen, Mette Kristensen, Arne Astrup

Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance

submitted by: tekn-ada
Background: Differential gene expression in adipose tissue during diet-induced weight loss followed by a weight stability period is poorly characterized. Markers of these processes may provide a deeper understanding of underlying mechanisms. Objective: We aimed to identify differentially expressed genes in human adipose tissue during weight loss and weight maintenance after weight loss. Design: RNA from subcutaneous abdominal adipose tissue from 9 obese subjects was analyzed by using a...
Authors: Lovisa Johansson, Anders Danielsson, Hemang Parikh, Maria Klintenberg, Fredrik Norström, Leif Groop, Martin Ridderstråle

Effects of 4 weight-loss diets differing in fat, protein, and carbohydrate on fat mass, lean mass, visceral adipose tissue, and hepatic fat: results from the POUNDS LOST trial.

submitted by: rdesouza
BACKGROUND: Weight loss reduces body fat and lean mass, but whether these changes are influenced by macronutrient composition of the diet is unclear. OBJECTIVE: We determined whether energy-reduced diets that emphasize fat, protein, or carbohydrate differentially reduce total, visceral, or hepatic fat or preserve lean mass. DESIGN: In a subset of participants in a randomized trial of 4 weight-loss diets, body fat and lean mass (n = 424; by using dual-energy X-ray absorptiometry) and...
Authors: RJ de Souza, GA Bray, VJ Carey, KD Hall, MS Leboff, CM Loria, NM Laranjo, FM Sacks, SR Smith