Urinary a-carboxyethyl hydroxychroman can be used as a predictor of a-tocopherol adequacy, as demonstrated in the Energetics Study

submitted by: mtraber
Background: Other than the in vitro erythrocyte hemolysis test, no valid biomarkers of vitamin E status currently exist. Objective: We hypothesized that the urinary vitamin E metabolite a-carboxyethyl hydroxychroman (a-CEHC) could serve as a biomarker. Design: The relations between urinary a-CEHC, plasma a-tocopherol, and vitamin E intakes were assessed by using a previously validated multipass, Web-based, 24-h self-administered dietary recall, and we concurrently collected plasma and...
Authors: Katie M Lebold, Alfonso Ang, Maret G Traber, Lenore Arab