Effects of vitamin C and D administration on mood and distress in acutely hospitalized patients

submitted by: LJHOFFER
Background: Hypovitaminosis C and D are highly prevalent in acute-care hospitals. Malnutrition with regard to these vitamins has been linked to mood disturbance and cognitive dysfunction. Objective: To determine whether vitamin C or D supplementation improves mood state or reduces psychological distress in acutely hospitalized patients with a high prevalence of hypovitaminosis C and D. Methods: Randomized, double-blind, active-control clinical trial comparing the effect of vitamin C (500...
Authors: Yifan Yang, Xing Jian Liu, Line Robitaille, Shaun Eintracht, Elizabeth MacNamara, L. John Hoffer

Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: A randomized controlled trial

submitted by: petersonca
Background: Obese adolescents are at a greater risk for vitamin D deficiency because the vitamin is thought to be sequestered by excess adipose tissue. Poor vitamin D status has been associated with a higher prevalence of the metabolic syndrome and/or type 2 diabetes in both adults and adolescents. Objective: To determine in obese adolescents the efficacy and safety of 4000 IU/day of vitamin D3; and if subsequent increased circulating concentrations of 25 hydroxyvitamin D [(25(OH)D] are...
Authors: Anthony Belenchia, Aneesh Tosh, Laura Hillman, Catherine Peterson

Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis

submitted by: Laura Tripkovic
Background: Currently, there is a lack of clarity in the literature as to whether there is a definitive difference between the effects of vitamins D2 and D3 in the raising of serum 25-hydroxyvitamin D [25(OH)D]. Objective: The objective of this article was to report a systematic review and meta-analysis of randomized controlled trials (RCTs) that have directly compared the effects of vitamin D2 and vitamin D3 on serum 25(OH)D concentrations in humans. Design: The ISI Web of Knowledge...
Authors: Laura Tripkovic, Helen Lambert, Kathryn Hart, Colin P Smith, Giselda Bucca, Simon Penson, Gemma Chope, Elina Hypponen, Jacqueline Berry, Reinhold Vieth, Susan Lanham-New