Effects of vitamin C and D administration on mood and distress in acutely hospitalized patients

submitted by: LJHOFFER
Background: Hypovitaminosis C and D are highly prevalent in acute-care hospitals. Malnutrition with regard to these vitamins has been linked to mood disturbance and cognitive dysfunction. Objective: To determine whether vitamin C or D supplementation improves mood state or reduces psychological distress in acutely hospitalized patients with a high prevalence of hypovitaminosis C and D. Methods: Randomized, double-blind, active-control clinical trial comparing the effect of vitamin C (500...
Authors: Yifan Yang, Xing Jian Liu, Line Robitaille, Shaun Eintracht, Elizabeth MacNamara, L. John Hoffer

Diet composition is associated with endogenous formation of N-nitroso compounds in obese men

submitted by: silviagratz
Endogenous formation of carcinogenic N-nitroso compounds (NOC) occurs in the human gut. Red meat is considered the most important dietary component linked to NOC formation, although nitrate and vitamin C (VitC) also contribute. We previously showed that high-protein weight-loss diets increased fecal NOC and this was enhanced by simultaneous carbohydrate restriction. Although previous studies have focused on the effect of either 1 or 2 dietary components on endogenous NOC formation, no...
Authors: Grietje Holtrop, Alexandra M. Johnstone, Claire Fyfe, Silvia W. Gratz