Prospective cohort studies of vitamin B6 intake and colorectal cancer incidence: modification by time?

submitted by: zhang
BACKGROUND: The relation between vitamin B-6 intake and colorectal cancer risk remains uncertain. OBJECTIVE: We prospectively evaluated whether a higher vitamin B-6 intake in the remote past is more strongly associated with a lower risk of colorectal cancer than an intake in the recent past in the Nurses' Health Study and the Health Professionals Follow-Up Study. DESIGN: We assessed vitamin B-6 intake every 4 y by using validated food-frequency questionnaires and followed 86,440...
Authors: Xuehong Zhang, Jung Eun Lee, Jing Ma, Youjin Je, Kana Wu, Walter C. Willett, Charles S. Fuchs, Edward L. Giovannucci