Vision Changes after Spaceflight Are Related to Alterations in Folate– and Vitamin B-12–Dependent One-Carbon Metabolism

submitted by: szwart
Approximately 20% (7 of 38) of astronauts on International Space Station (ISS) missions have developed measurable ophthalmic changes after flight. This study was conducted to determine if the folate– and vitamin B-12?dependent 1-carbon metabolic pathway is altered in these individuals. Since 2006, we have conducted experiments on the ISS to evaluate nutritional status and related biochemical indices of astronauts before, during, and after flight. Data were modeled to evaluate differences...
Authors: Sara R. Zwart, C. Robert Gibson, Thomas H. Mader, Karen Ericson, Robert Ploutz-Snyder, Martina Heer, Scott M. Smith

The role of vision in detecting and correcting fingertip force errors during object lifting

submitted by: gbucking
Vision provides many reliable cues about the likely weight of an object, allowing individuals to predict how heavy it will be. The forces used to lift an object for the first time reflect these predictions. This, however, leads to inevitable errors during lifts of objects that weigh unexpected amounts. Fortunately, these errors are rarely made twice in a row—lifters have the impressive ability to detect and correct large or small misapplications of fingertip forces, even while experiencing...
Authors: Gavin Buckingham, Nathalie s. Ranger, Melvyn a. Goodale

Deactivation Mechanisms of Rod Phototransduction (The Cogan Lecture)

submitted by: arvojenny
The absorption of photons in rods and cones of the retina activate homologous biochemical signaling cascades that lead to the electrical changes that subserve the first steps in vision. Persistent activity of the cascade interferes with the ability of the photoreceptor to signal the absorption of subsequent photons, ultimately limiting the photoreceptor’s sensitivity and temporal resolution. This article summarizes recent work on transgenic and knockout mouse rods that have revealed the...
Authors: Marie Burns

Homeostatic Regulation of Photoreceptor Cell Integrity: Significance of the Potent Mediator Neuroprotectin D1 Biosynthesized from Docosahexaenoic Acid (The Proctor Lecture)

submitted by: arvojenny
Vision is sustained by a unique and beautiful relationship—that between photoreceptor cells and retinal pigment epithelial (RPE) cells. From the harmony of this cellular relationship emerges the life-long survival of the photoreceptor cell, despite the fact that the part of the eye where these cells interact is continuously exposed to potentially damaging factors. This relationship is one of the best examples of homeostasis in action as conceptualized for other cells and organs in 1932 by...
Authors: Nicolas Bazan

The Living Matrix

submitted by: thelivingmatrix
"The Living Matrix: The Science of Healing," trailer; The movie uncovers new ideas about the intricate web of factors that determine our health and interviews a group of dedicated scientists, psychologists, bioenergetic researchers and holistic practitioners, who are finding healing potential in new places. (The energetic information-based medicine looks particularly powerful.)