Synaptic Land - The Movie

submitted by: KidsJudgePartnership
The story of how two behavioral neuroscience graduate students from Oregon Health & Science University conceived and constructed the very first "Synaptic Land", a game that helps kids learn about processes involved in neurotransmission. Since its debut at the Oregon Kids Judge! Neuroscience Fair held at OMSI in 2002, undergraduate and graduate students at many other universities have created their own versions of the Synaptic Land game (e.g., PENN, University of Scranton, California...

Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge

submitted by: JCB
Chemoattractant signaling induces the polarization and directed movement of cells secondary to the activation of multiple effector pathways. In addition, chemotactic signals can be amplified and relayed to proximal cells via the synthesis and secretion of additional chemoattractant. The mechanisms underlying such remarkable features remain ill defined. We show that the asymmetrical distribution of adenylyl cyclase (ACA) at the back of Dictyostelium discoideum cells, an essential determinant...
Authors: Paul Kriebel, Valarie Barr, Erin Rericha, Guofeng Zhang, Carole Parent